The ESCRT protein CHMP5 promotes T cell leukemia by enabling BRD4-p300-dependent transcription.
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| Title: | The ESCRT protein CHMP5 promotes T cell leukemia by enabling BRD4-p300-dependent transcription. |
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| Authors: | Umphred-Wilson K; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Ratnayake S; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Tang Q; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China., Wang R; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China., Chaudhary SG; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Ballachanda DN; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Trichka J; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Wisniewski J; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Zhou L; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 77030, USA., Chen Q; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Meerzaman D; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Singer DS; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Adoro S; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. stanley.adoro@nih.gov. |
| Source: | Nature communications [Nat Commun] 2025 May 03; Vol. 16 (1), pp. 4133. Date of Electronic Publication: 2025 May 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-59504-9 |
