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The ESCRT protein CHMP5 promotes T cell leukemia by enabling BRD4-p300-dependent transcription.

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Title: The ESCRT protein CHMP5 promotes T cell leukemia by enabling BRD4-p300-dependent transcription.
Authors: Umphred-Wilson K; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Ratnayake S; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Tang Q; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China., Wang R; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China., Chaudhary SG; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Ballachanda DN; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Trichka J; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA., Wisniewski J; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Zhou L; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 77030, USA., Chen Q; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Meerzaman D; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA., Singer DS; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA., Adoro S; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. stanley.adoro@nih.gov.
Source: Nature communications [Nat Commun] 2025 May 03; Vol. 16 (1), pp. 4133. Date of Electronic Publication: 2025 May 03.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Umphred-Wilson+K%22">Umphred-Wilson K</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.<br /><searchLink fieldCode="AU" term="%22Ratnayake+S%22">Ratnayake S</searchLink>; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Tang+Q%22">Tang Q</searchLink>; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Wang+R%22">Wang R</searchLink>; College of Animal Science and Technology, Sichuan Agricultural University, 611130, Chengdu, China.<br /><searchLink fieldCode="AU" term="%22Chaudhary+SG%22">Chaudhary SG</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Ballachanda+DN%22">Ballachanda DN</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Trichka+J%22">Trichka J</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.; Immunology Training Program, Department of Pathology, Case Western Reserve University School of Medicine, Cleveland, OH, 44106, USA.<br /><searchLink fieldCode="AU" term="%22Wisniewski+J%22">Wisniewski J</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Zhou+L%22">Zhou L</searchLink>; Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, 77030, USA.<br /><searchLink fieldCode="AU" term="%22Chen+Q%22">Chen Q</searchLink>; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Meerzaman+D%22">Meerzaman D</searchLink>; Computational Genomics and Bioinformatics Branch, Center for Biomedical Informatics & Information Technology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20850, USA.<br /><searchLink fieldCode="AU" term="%22Singer+DS%22">Singer DS</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.<br /><searchLink fieldCode="AU" term="%22Adoro+S%22">Adoro S</searchLink>; Experimental Immunology Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA. stanley.adoro@nih.gov.
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