Maintaining ventilation with very low tidal volume and positive-end expiratory pressure versus no ventilation during cardiopulmonary bypass for cardiac surgery in adults: a randomized clinical trial.
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| Title: | Maintaining ventilation with very low tidal volume and positive-end expiratory pressure versus no ventilation during cardiopulmonary bypass for cardiac surgery in adults: a randomized clinical trial. |
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| Authors: | Tadié JM; Department of Infectious Diseases and Intensive Care Unit, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France. jeanmarc.tadie@chu-rennes.fr.; SITI Laboratory, UMR U1236, INSERM, University of Rennes, EFS, Rennes University Hospital, Rennes, France. jeanmarc.tadie@chu-rennes.fr.; Centre d'investigation Clinique de Rennes (CIC1414), Inserm, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France. jeanmarc.tadie@chu-rennes.fr., Ouattara A; Department of Cardiovascular Anaesthesia and Critical Care, CHU Bordeaux, Magellan Medico-Surgical Centre, Bordeaux, France.; UMR 1034, Biology of Cardiovascular Diseases, Univ. Bordeaux, INSERM, Pessac, France., Laviolle B; CHU Rennes, Univ Rennes, Inserm, UMR_S 1085 (IRSET), CIC 1414, Rennes, France., Lesouhaitier M; Department of Infectious Diseases and Intensive Care Unit, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France.; SITI Laboratory, UMR U1236, INSERM, University of Rennes, EFS, Rennes University Hospital, Rennes, France.; Centre d'investigation Clinique de Rennes (CIC1414), Inserm, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France., Esvan M; Centre d'investigation Clinique de Rennes (CIC1414), Inserm, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France., Rousseau C; Centre d'investigation Clinique de Rennes (CIC1414), Inserm, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France., Grégoire M; SITI Laboratory, UMR U1236, INSERM, University of Rennes, EFS, Rennes University Hospital, Rennes, France., Gaudriot B; Department of Anesthesia and Critical Care, Pontchaillou, Rennes University Hospital, Rennes, France., Nesseler N; Department of Anesthesia and Critical Care, Pontchaillou, Rennes University Hospital, Rennes, France., Labaste F; Anesthesiology and Intensive Care Department, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Sanchez P; Anesthesiology and Intensive Care Department, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Marcheix B; Department of Cardiovascular Surgery, Centre Hospitalier Universitaire de Toulouse, Toulouse, France., Beurton A; Department of Cardiovascular Anaesthesia and Critical Care, CHU Bordeaux, Magellan Medico-Surgical Centre, Bordeaux, France.; UMR 1034, Biology of Cardiovascular Diseases, Univ. Bordeaux, INSERM, Pessac, France., Dureau P; Department of Anesthesiology and Critical Care Medicine, Sorbonne University, Cardiology Institute, GRC 29, Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France., Demondion P; Thoracic and Cardiovascular Surgery Department, Groupe Hospitalier Pitié-Salpétrière, Institute of Cardiology, Sorbonne Université, APHP, Paris, France., Fouquet O; Department of Cardiac Surgery, University Hospital of Angers, Angers, France., Rineau E; Department of Anesthesiology and Critical Care, Angers University, Angers, France., Amour J; Institute of Perfusion, Critical Care Medicine and Anesthesiology in Cardiac Surgery Paris Sud (IPRA), Hôpital Privé Jacques Cartier, Ramsay Health Care, Massy, France., Verhoye JP; Department of Vascular and Cardio-Thoracic Surgery, Rennes University Hospital, Rennes, France., Mercat A; Medical Intensive Care Unit, Vent'Lab, Angers University Hospital, University of Angers, 4 Rue Larrey, Angers, France., Terzi N; Department of Infectious Diseases and Intensive Care Unit, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France.; Centre d'investigation Clinique de Rennes (CIC1414), Inserm, Centre Hospitalier Universitaire Rennes, Université de Rennes 1, Rennes, France., Tarte K; SITI Laboratory, UMR U1236, INSERM, University of Rennes, EFS, Rennes University Hospital, Rennes, France., Bouglé A; Department of Anesthesiology and Critical Care Medicine, Sorbonne University, Cardiology Institute, GRC 29, Assistance Publique - Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France., Flecher E; Department of Vascular and Cardio-Thoracic Surgery, Rennes University Hospital, Rennes, France. |
| Corporate Authors: | VECAR Trial Group and REVA |
| Source: | Intensive care medicine [Intensive Care Med] 2025 May; Vol. 51 (5), pp. 849-860. Date of Electronic Publication: 2025 May 05. |
| Publication Type: | Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: Springer Verlag Country of Publication: United States NLM ID: 7704851 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1238 (Electronic) Linking ISSN: 03424642 NLM ISO Abbreviation: Intensive Care Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1432-1238 |
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| DOI: | 10.1007/s00134-025-07901-5 |
