The PARP inhibitor olaparib promotes senescence in murine macrophages.

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Title: The PARP inhibitor olaparib promotes senescence in murine macrophages.
Authors: Kieronska-Rudek A; Section of Pharmacology, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland., Zuhra K; Section of Pharmacology, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland., Ascenção K; Section of Pharmacology, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland., Chlopicki S; Jagiellonian Centre for Experimental Therapeutics, Jagiellonian University, Krakow, Poland., Szabo C; Section of Pharmacology, Department of Oncology, Microbiology and Immunology, Faculty of Science and Medicine, University of Fribourg, Fribourg, Switzerland. csaba.szabo@unifr.ch.
Source: GeroScience [Geroscience] 2026 Feb; Vol. 48 (1), pp. 755-775. Date of Electronic Publication: 2025 May 06.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Springer International Publishing Country of Publication: Switzerland NLM ID: 101686284 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2509-2723 (Electronic) Linking ISSN: 25092723 NLM ISO Abbreviation: Geroscience Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2509-2723
DOI:10.1007/s11357-025-01679-6