A phase 1/2a clinical trial to assess safety and immunogenicity of an adenoviral-vectored capsular group B meningococcal vaccine.
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| Title: | A phase 1/2a clinical trial to assess safety and immunogenicity of an adenoviral-vectored capsular group B meningococcal vaccine. |
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| Authors: | Dold C; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Oguti B; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK.; Division of Infection and Immunity, Faculty of Medical Sciences, University College London, London WC1E 6JF, UK., Silva-Reyes L; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Stanzelova A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Raymond M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Smith CC; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Moore M; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Barton A; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Choi EM; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Plested E; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Tanha K; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Louth J; Vaccine Evaluation Unit, UK Health Security Agency, Manchester M13 9WL, UK., Holland A; Vaccine Evaluation Unit, UK Health Security Agency, Manchester M13 9WL, UK., Cook R; Vaccine Evaluation Unit, UK Health Security Agency, Manchester M13 9WL, UK., King J; Vaccine Evaluation Unit, UK Health Security Agency, Manchester M13 9WL, UK., Lucidarme J; Meningococcal Reference Unit, UK Health Security Agency, Manchester M13 9WL, UK., Borrow R; Vaccine Evaluation Unit, UK Health Security Agency, Manchester M13 9WL, UK.; Meningococcal Reference Unit, UK Health Security Agency, Manchester M13 9WL, UK., Hill AVS; Jenner Institute, University of Oxford, Old Road Campus Research Building, Oxford OX3 7DQ, UK., Beernink PT; Department of Paediatrics, University of California, San Francisco, San Francisco, CA 94143, USA., Liu X; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Pollard AJ; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK., Rollier CS; Oxford Vaccine Group, Department of Paediatrics, University of Oxford and NIHR Oxford Biomedical Research Centre, CCVTM, Churchill Lane, Oxford OX37LE, UK.; School of Biosciences, Faculty of Health and Medical Sciences, University of Surrey, Guildford GU2 7XH, UK. |
| Source: | Science translational medicine [Sci Transl Med] 2025 May 07; Vol. 17 (797), pp. eadn1441. Date of Electronic Publication: 2025 May 07. |
| Publication Type: | Journal Article; Clinical Trial, Phase I; Clinical Trial, Phase II |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1946-6242 |
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| DOI: | 10.1126/scitranslmed.adn1441 |
