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Age-stratified machine learning identifies divergent prognostic significance of molecular alterations in AML.

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Title: Age-stratified machine learning identifies divergent prognostic significance of molecular alterations in AML.
Authors: Eckardt JN; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; Else Kröner Fresenius Center for Digital Health TUD Dresden University of Technology Dresden Germany., Hahn W; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig Dresden Germany.; Institute for Medical Informatics and Biometry TUD Dresden University of Technology Dresden Germany., Ries RE; Translational Science and Therapeutics Division Fred Hutchinson Cancer Research Center Seattle Washington USA.; Division of Hematology and Oncology Seattle Children's Hospital Seattle Washington USA., Chrost SD; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Winter S; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Stasik S; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Röllig C; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Platzbecker U; Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Disease University of Leipzig Medical Center Leipzig Germany., Müller-Tidow C; Department of Medicine V University Hospital Heidelberg Heidelberg Germany., Serve H; Department of Medicine 2, Hematology and Oncology Goethe University Frankfurt Frankfurt Germany., Baldus CD; Department of Hematology and Oncology University Hospital Schleswig Holstein Kiel Germany., Schliemann C; Department of Medicine A University Hospital Münster Münster Germany., Schäfer-Eckart K; Department of Internal Medicine V Paracelsus Medizinische Privatuniversität and University Hospital Nürnberg Nürnberg Germany., Hanoun M; Department of Hematology University Hospital Essen Essen Germany., Kaufmann M; Department of Hematology, Oncology and Palliative Care Robert Bosch Hospital Stuttgart Germany., Burchert A; Department of Hematology, Oncology and Immunology Philipps-University Marburg Marburg Germany., Schetelig J; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Bornhäuser M; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; German Cancer Consortium (DKTK), Partner Site Dresden German Cancer Research Center (DKFZ) Heidelberg Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR) Germany., Wolfien M; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig Dresden Germany.; Institute for Medical Informatics and Biometry TUD Dresden University of Technology Dresden Germany., Meshinchi S; Translational Science and Therapeutics Division Fred Hutchinson Cancer Research Center Seattle Washington USA.; Division of Hematology and Oncology Seattle Children's Hospital Seattle Washington USA., Thiede C; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany., Middeke JM; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; Else Kröner Fresenius Center for Digital Health TUD Dresden University of Technology Dresden Germany.
Source: HemaSphere [Hemasphere] 2025 May 07; Vol. 9 (5), pp. e70132. Date of Electronic Publication: 2025 May 07 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 101740619 Publication Model: eCollection Cited Medium: Internet ISSN: 2572-9241 (Electronic) Linking ISSN: 25729241 NLM ISO Abbreviation: Hemasphere Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Age-stratified machine learning identifies divergent prognostic significance of molecular alterations in AML.
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  Data: <searchLink fieldCode="AU" term="%22Eckardt+JN%22">Eckardt JN</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; Else Kröner Fresenius Center for Digital Health TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Hahn+W%22">Hahn W</searchLink>; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig Dresden Germany.; Institute for Medical Informatics and Biometry TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Ries+RE%22">Ries RE</searchLink>; Translational Science and Therapeutics Division Fred Hutchinson Cancer Research Center Seattle Washington USA.; Division of Hematology and Oncology Seattle Children's Hospital Seattle Washington USA.<br /><searchLink fieldCode="AU" term="%22Chrost+SD%22">Chrost SD</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Winter+S%22">Winter S</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Stasik+S%22">Stasik S</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Röllig+C%22">Röllig C</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Platzbecker+U%22">Platzbecker U</searchLink>; Department of Hematology, Cellular Therapy, Hemostaseology and Infectious Disease University of Leipzig Medical Center Leipzig Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Tidow+C%22">Müller-Tidow C</searchLink>; Department of Medicine V University Hospital Heidelberg Heidelberg Germany.<br /><searchLink fieldCode="AU" term="%22Serve+H%22">Serve H</searchLink>; Department of Medicine 2, Hematology and Oncology Goethe University Frankfurt Frankfurt Germany.<br /><searchLink fieldCode="AU" term="%22Baldus+CD%22">Baldus CD</searchLink>; Department of Hematology and Oncology University Hospital Schleswig Holstein Kiel Germany.<br /><searchLink fieldCode="AU" term="%22Schliemann+C%22">Schliemann C</searchLink>; Department of Medicine A University Hospital Münster Münster Germany.<br /><searchLink fieldCode="AU" term="%22Schäfer-Eckart+K%22">Schäfer-Eckart K</searchLink>; Department of Internal Medicine V Paracelsus Medizinische Privatuniversität and University Hospital Nürnberg Nürnberg Germany.<br /><searchLink fieldCode="AU" term="%22Hanoun+M%22">Hanoun M</searchLink>; Department of Hematology University Hospital Essen Essen Germany.<br /><searchLink fieldCode="AU" term="%22Kaufmann+M%22">Kaufmann M</searchLink>; Department of Hematology, Oncology and Palliative Care Robert Bosch Hospital Stuttgart Germany.<br /><searchLink fieldCode="AU" term="%22Burchert+A%22">Burchert A</searchLink>; Department of Hematology, Oncology and Immunology Philipps-University Marburg Marburg Germany.<br /><searchLink fieldCode="AU" term="%22Schetelig+J%22">Schetelig J</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Bornhäuser+M%22">Bornhäuser M</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; German Cancer Consortium (DKTK), Partner Site Dresden German Cancer Research Center (DKFZ) Heidelberg Germany.; National Center for Tumor Diseases (NCT), NCT/UCC Dresden, a partnership between DKFZ Faculty of Medicine and University Hospital Carl Gustav Carus, TUD Dresden University of Technology, and Helmholtz-Zentrum Dresden-Rossendorf (HZDR) Germany.<br /><searchLink fieldCode="AU" term="%22Wolfien+M%22">Wolfien M</searchLink>; Center for Scalable Data Analytics and Artificial Intelligence (ScaDS.AI) Dresden/Leipzig Dresden Germany.; Institute for Medical Informatics and Biometry TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Meshinchi+S%22">Meshinchi S</searchLink>; Translational Science and Therapeutics Division Fred Hutchinson Cancer Research Center Seattle Washington USA.; Division of Hematology and Oncology Seattle Children's Hospital Seattle Washington USA.<br /><searchLink fieldCode="AU" term="%22Thiede+C%22">Thiede C</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.<br /><searchLink fieldCode="AU" term="%22Middeke+JM%22">Middeke JM</searchLink>; Department of Internal Medicine I University Hospital Carl Gustav Carus, TUD Dresden University of Technology Dresden Germany.; Else Kröner Fresenius Center for Digital Health TUD Dresden University of Technology Dresden Germany.
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