JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine.
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| Title: | JAK-STAT inhibitory effect of IN-115314, a novel small molecule inhibitor, and pharmacokinetic/pharmacodynamic study in canine. |
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| Authors: | Ahn JH; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kim J; HK inno.N Corporation, Seoul, Republic of Korea.; Department of Biological Sciences, Konkuk University, Seoul, Republic of Korea., Kwak J; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Kim J; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Lee NY; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Department of Veterinary Pathology and Research Institute of Veterinary Science, College of Veterinary Medicine, Seoul National University, Seoul, Republic of Korea., Choi H; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Bae HJ; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea., Cho SH; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Jung SG; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon HM; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kwon E; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea., Kim D; HK inno.N Corporation, Seoul, Republic of Korea., Kim M; HK inno.N Corporation, Seoul, Republic of Korea., Yoon D; HK inno.N Corporation, Seoul, Republic of Korea., Kim S; HK inno.N Corporation, Seoul, Republic of Korea., Kim B; HK inno.N Corporation, Seoul, Republic of Korea., Kang BC; Department of Experiment Animal Research, Biomedical Research Institute, Seoul National University Hospital, Seoul, Republic of Korea.; Graduate School of Translational Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea. |
| Source: | British journal of pharmacology [Br J Pharmacol] 2025 Oct; Vol. 182 (20), pp. 5071-5082. Date of Electronic Publication: 2025 May 07. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: England NLM ID: 7502536 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5381 (Electronic) Linking ISSN: 00071188 NLM ISO Abbreviation: Br J Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-5381 |
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| DOI: | 10.1111/bph.70055 |
