HDX-MS reveals pH and temperature-responsive regions on AAV capsids and the structural basis for DNA release.
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| Title: | HDX-MS reveals pH and temperature-responsive regions on AAV capsids and the structural basis for DNA release. |
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| Authors: | Ye X; Regeneron Pharmaceuticals Inc., Tarrytown, NY, 10591-6707, USA. xiang.ye@regeneron.com., Hu M; Regeneron Pharmaceuticals Inc., Tarrytown, NY, 10591-6707, USA., Hu Y; Regeneron Pharmaceuticals Inc., Tarrytown, NY, 10591-6707, USA. yunli.hu@regeneron.com., Qiu H; Regeneron Pharmaceuticals Inc., Tarrytown, NY, 10591-6707, USA., Li N; Regeneron Pharmaceuticals Inc., Tarrytown, NY, 10591-6707, USA. |
| Source: | Gene therapy [Gene Ther] 2025 Dec; Vol. 32 (6), pp. 621-631. Date of Electronic Publication: 2025 May 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 9421525 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5462 (Electronic) Linking ISSN: 09697128 NLM ISO Abbreviation: Gene Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1476-5462 |
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| DOI: | 10.1038/s41434-025-00539-4 |
