Comprehensive synthesis and anticoagulant evaluation of a diverse fucoidan library.

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Title: Comprehensive synthesis and anticoagulant evaluation of a diverse fucoidan library.
Authors: Chen SC; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China., Qin X; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China., Xiong N; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China., Lin L; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China., Wu Y; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China., Li Q; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China., Sun D; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China., Xiong DC; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China., Callmann CE; Department of Chemistry, The University of Texas at Austin, Austin, TX, US., Wu M; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China. wumingyi@mail.kib.ac.cn., Ye XS; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China. xinshan@bjmu.edu.cn.
Source: Nature communications [Nat Commun] 2025 May 10; Vol. 16 (1), pp. 4364. Date of Electronic Publication: 2025 May 10.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
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  Data: Comprehensive synthesis and anticoagulant evaluation of a diverse fucoidan library.
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  Data: <searchLink fieldCode="AU" term="%22Chen+SC%22">Chen SC</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Qin+X%22">Qin X</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.; State Key Laboratory of Natural Medicines, School of Traditional Chinese Pharmacy, China Pharmaceutical University, Nanjing, China.<br /><searchLink fieldCode="AU" term="%22Xiong+N%22">Xiong N</searchLink>; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Lin+L%22">Lin L</searchLink>; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China.<br /><searchLink fieldCode="AU" term="%22Wu+Y%22">Wu Y</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+Q%22">Li Q</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Sun+D%22">Sun D</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Xiong+DC%22">Xiong DC</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Callmann+CE%22">Callmann CE</searchLink>; Department of Chemistry, The University of Texas at Austin, Austin, TX, US.<br /><searchLink fieldCode="AU" term="%22Wu+M%22">Wu M</searchLink>; State Key Laboratory of Phytochemistry and Natural Medicines, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming, China. wumingyi@mail.kib.ac.cn.<br /><searchLink fieldCode="AU" term="%22Ye+XS%22">Ye XS</searchLink>; State Key Laboratory of Natural and Biomimetic Drugs, School of Pharmaceutical Sciences, and Chemical Biology Center, Peking University, Beijing, China. xinshan@bjmu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101528555%22">Nature communications</searchLink> [Nat Commun] 2025 May 10; Vol. 16 (1), pp. 4364. <i>Date of Electronic Publication: </i>2025 May 10.
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              Text: 2025 May 10
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