CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial.

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Title: CRISPR/Cas9-engineering of Kell null erythrocytes to unveil host targeted irresistible antimalarial.
Authors: Kumari G; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India., Gupta P; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Goswami SG; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Jain R; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India., Anand S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India., Biswas S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India., Garg S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India., Thakur P; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Saravanakumar V; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India., Arvinden VR; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India., Goswami B; Agartala Government Medical college, Agartala, Tripura, India., Bhowmick IP; ICMR-Regional Medical Research Centre, Northeast Region (RMRC-NE), Dibrugarh, Assam, India.; Model Rural Health Research Unit (MRHRU), Tripura, India., Mohandas N; Laboratory of Red Cell Physiology, New York Blood Center, 310 E 67th St, New York, NY, 10065, USA., Burrows J; Medicines for Malaria Venture, Geneva, Switzerland., Ramalingam S; CSIR- Institute of Genomics and Integrative Biology, Mathura Road, Sukhdev Vihar, New Delhi, 110025, India. sivaramalingam@igib.res.in.; Academy of Scientific and Innovative Research (AcSIR), Ghaziabad, 201002, India. sivaramalingam@igib.res.in.; Department of Biological Sciences and Bioengineering, Mehta Family Centre for Engineering in Medicine, Indian Institute of Technology, Kanpur, India. sivaramalingam@igib.res.in., Singh S; Special Centre for Molecular Medicine, Jawaharlal Nehru University, New Delhi, 110067, India. shailja.jnu@gmail.com.
Source: Communications biology [Commun Biol] 2025 May 11; Vol. 8 (1), pp. 730. Date of Electronic Publication: 2025 May 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2399-3642
DOI:10.1038/s42003-025-07968-2