Structural proteomics defines a sequential priming mechanism for the progesterone receptor.

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Title: Structural proteomics defines a sequential priming mechanism for the progesterone receptor.
Authors: Mann MD; Skaggs Graduate School of Chemical and Biological Sciences, Scripps Research, La Jolla, CA, USA.; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA., Wang M; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Ferreon JC; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Tsoi PS; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Suess MP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Jain A; Mass Spectrometry Proteomics Core Facility. Advanced Technology Cores, Baylor College of Medicine, Houston, TX, USA., Malovannaya A; Verna and Marrs McLean Department of Biochemistry and Molecular Pharmacology, Baylor College of Medicine, Houston, TX, USA., Alvarez RV; Omics Informatics LLC, Honolulu, HI, USA., Pascal BD; Omics Informatics LLC, Honolulu, HI, USA., Kumar R; Department of Pharmaceutical and Biomedical Sciences, Touro College of Pharmacy, Touro University, New York, NY, USA., Edwards DP; Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, TX, USA., Griffin PR; Skaggs Graduate School of Chemical and Biological Sciences, Scripps Research, La Jolla, CA, USA. pgriffin2@ufl.edu.; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA. pgriffin2@ufl.edu.
Source: Nature communications [Nat Commun] 2025 May 12; Vol. 16 (1), pp. 4403. Date of Electronic Publication: 2025 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-59458-y