Fast product release requires active-site water dynamics in carbonic anhydrase.
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| Title: | Fast product release requires active-site water dynamics in carbonic anhydrase. |
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| Authors: | Kim JK; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea.; Frontier of Extreme Physics, Korea Research Institute of Standards and Science, Daejeon, 34113, Republic of Korea., Lim SW; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Jeong H; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Lee C; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Kim S; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Son DW; Division of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju, 52828, Republic of Korea.; Anti-Aging Bio Cell Factory Regional Leading Research Center (ABC-RLRC), Gyeongsang National University, Jinju, 52828, Republic of Korea., Kumar R; Department of Chemistry, Pusan National University, Busan, 46241, Republic of Korea.; Chemistry Institute for Functional Materials, Pusan National University, Busan, 46241, Republic of Korea., Andring JT; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA., Lomelino C; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA., Wierman JL; Cornell High Energy Synchrotron Source, Cornell University, Ithaca, New York, 14853, USA., Cohen AE; Stanford Synchrotron Radiation Lightsource, SLAC National Accelerator Laboratory, Menlo Park, California, 94025, USA., Shin TJ; Graduate School of Semiconductor Materials and Devices Engineering, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Ghim CM; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., McKenna R; Department of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL, 32610, USA., Jo BH; Division of Applied Life Science (BK21 Four), Gyeongsang National University, Jinju, 52828, Republic of Korea.; Anti-Aging Bio Cell Factory Regional Leading Research Center (ABC-RLRC), Gyeongsang National University, Jinju, 52828, Republic of Korea.; Research Institute of Life Science, Gyeongsang National University, Jinju, 52828, Republic of Korea., Min D; Department of Chemistry, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea., Choi JM; Department of Chemistry, Pusan National University, Busan, 46241, Republic of Korea.; Chemistry Institute for Functional Materials, Pusan National University, Busan, 46241, Republic of Korea., Kim CU; Department of Physics, Ulsan National Institute of Science and Technology (UNIST), Ulsan, 44919, Republic of Korea. cukim@unist.ac.kr. |
| Source: | Nature communications [Nat Commun] 2025 May 12; Vol. 16 (1), pp. 4404. Date of Electronic Publication: 2025 May 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-59645-x |