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An integrated transcriptomic cell atlas of human endoderm-derived organoids.

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Title: An integrated transcriptomic cell atlas of human endoderm-derived organoids.
Authors: Xu Q; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. quan.xu@roche.com., Halle L; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Hediyeh-Zadeh S; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Life Sciences, Technical University of Munich, Munich, Germany., Kuijs M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Riedweg R; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Kilik U; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland., Recaldin T; Roche Innovation Center Basel, Roche Pharma Research and Early Development, Basel, Switzerland., Yu Q; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Rall I; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Frum T; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA., Adam L; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Parikh S; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Life Sciences, Technical University of Munich, Munich, Germany., Kfuri-Rubens R; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; IIIrd Medical Department, Klinikum rechts der Isar, Munich, Germany.; School of Medicine, Technical University of Munich, Munich, Germany., Gander M; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Klein D; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany., Curion F; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany.; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany., He Z; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland., Fleck JS; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Oost K; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Kahnwald M; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Barbiero S; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Mitrofanova O; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Maciag GJ; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark., Jensen KB; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark., Lutolf M; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Liberali P; Biozentrum, University of Basel, Basel, Switzerland.; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland., Spence JR; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan College of Engineering, Ann Arbor, MI, USA., Gjorevski N; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Beumer J; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland., Treutlein B; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch., Theis FJ; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Life Sciences, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de., Camp JG; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.
Source: Nature genetics [Nat Genet] 2025 May; Vol. 57 (5), pp. 1201-1212. Date of Electronic Publication: 2025 May 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE
Database: MEDLINE Ultimate
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Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Biozentrum, University of Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Recaldin+T%22">Recaldin T</searchLink>; Roche Innovation Center Basel, Roche Pharma Research and Early Development, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Yu+Q%22">Yu Q</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Rall+I%22">Rall I</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Frum+T%22">Frum T</searchLink>; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Adam+L%22">Adam L</searchLink>; 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Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Maciag+GJ%22">Maciag GJ</searchLink>; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Jensen+KB%22">Jensen KB</searchLink>; Novo Nordisk Foundation Center for Stem Cell Medicine, reNEW, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Lutolf+M%22">Lutolf M</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.; Laboratory of Stem Cell Bioengineering, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland.<br /><searchLink fieldCode="AU" term="%22Liberali+P%22">Liberali P</searchLink>; Biozentrum, University of Basel, Basel, Switzerland.; Friedrich Miescher Institute for Biomedical Research (FMI), Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Spence+JR%22">Spence JR</searchLink>; Department of Internal Medicine, Division of Gastroenterology and Hepatology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Cell and Developmental Biology, University of Michigan Medical School, Ann Arbor, MI, USA.; Department of Biomedical Engineering, University of Michigan College of Engineering, Ann Arbor, MI, USA.<br /><searchLink fieldCode="AU" term="%22Gjorevski+N%22">Gjorevski N</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Beumer+J%22">Beumer J</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Treutlein+B%22">Treutlein B</searchLink>; Department of Biosystems Science and Engineering, ETH Zürich, Basel, Switzerland. barbara.treutlein@bsse.ethz.ch.<br /><searchLink fieldCode="AU" term="%22Theis+FJ%22">Theis FJ</searchLink>; Department of Computational Health, Institute of Computational Biology, Helmholtz Center Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Life Sciences, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.; School of Computation, Information and Technology, Technical University of Munich, Munich, Germany. fabian.theis@helmholtz-munich.de.<br /><searchLink fieldCode="AU" term="%22Camp+JG%22">Camp JG</searchLink>; Institute of Human Biology (IHB), Roche Pharma Research and Early Development, Roche Innovation Center, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.; Biozentrum, University of Basel, Basel, Switzerland. jarrettgrayson.camp@unibas.ch.
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  Data: <searchLink fieldCode="JN" term="%229216904%22">Nature genetics</searchLink> [Nat Genet] 2025 May; Vol. 57 (5), pp. 1201-1212. <i>Date of Electronic Publication: </i>2025 May 12.
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