Shear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosis.

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Bibliographic Details
Title: Shear-dependent platelet aggregation by ChAdOx1 nCoV-19 vaccine: a novel biophysical mechanism for arterial thrombosis.
Authors: Chen YC; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia., Louis NELR; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia., Huang A; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia., Sun A; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.; Heart Research Institute, Newtown, NSW, Australia.; The University of Sydney Nano Institute, The University of Sydney, Camperdown, NSW, Australia., Dupuy A; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.; The University of Sydney Nano Institute, The University of Sydney, Camperdown, NSW, Australia., Moldovan L; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.; Heart Research Institute, Newtown, NSW, Australia., Pelaia T; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia., Ren J; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia., Cohen TS; Vaccines and Immune Therapies, Biopharmaceuticals R&D, AstraZeneca, Gaithersburg, MD., Gilbert SC; Pandemic Sciences Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom., Tran H; Department of Clinical Haematology, Alfred Hospital, Melbourne, VIC, Australia., Peter K; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.; Baker Department of Cardiometabolic Health, University of Melbourne, Melbourne, VIC, Australia.; School of Translational Medicine, Monash University, Melbourne, VIC, Australia., McFadyen JD; Atherothrombosis and Vascular Biology, Baker Heart and Diabetes Institute, Melbourne, VIC, Australia.; Department of Clinical Haematology, Alfred Hospital, Melbourne, VIC, Australia.; Baker Department of Cardiometabolic Health, University of Melbourne, Melbourne, VIC, Australia.; School of Translational Medicine, Monash University, Melbourne, VIC, Australia., Ju LA; School of Biomedical Engineering, The University of Sydney, Darlington, NSW, Australia.; Charles Perkins Centre, The University of Sydney, Camperdown, NSW, Australia.; Heart Research Institute, Newtown, NSW, Australia.; The University of Sydney Nano Institute, The University of Sydney, Camperdown, NSW, Australia.
Source: Blood [Blood] 2025 Jul 24; Vol. 146 (4), pp. 496-503.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 7603509 Publication Model: Print Cited Medium: Internet ISSN: 1528-0020 (Electronic) Linking ISSN: 00064971 NLM ISO Abbreviation: Blood Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1528-0020
DOI:10.1182/blood.2024027675