Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice.

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Title: Mucosal unadjuvanted booster vaccines elicit local IgA responses by conversion of pre-existing immunity in mice.
Authors: Kwon DI; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA.; Howard Hughes Medical Institute, Chevy Chase, MD, USA., Mao T; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Israelow B; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA.; Section of Infectious Diseases, Department of Medicine, Yale School of Medicine, New Haven, CT, USA., Santos Guedes de Sá K; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA., Dong H; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA.; Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA., Iwasaki A; Department of Immunobiology, Yale School of Medicine, New Haven, CT, USA. akiko.iwasaki@yale.edu.; Center for Infection and Immunity, Yale School of Medicine, New Haven, CT, USA. akiko.iwasaki@yale.edu.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. akiko.iwasaki@yale.edu.
Source: Nature immunology [Nat Immunol] 2025 Jun; Vol. 26 (6), pp. 908-919. Date of Electronic Publication: 2025 May 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2916
DOI:10.1038/s41590-025-02156-0