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CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.

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Bibliographic Details
Title: CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.
Authors: Cahn JKB; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA., Ludwicki H; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Shingler J; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Gulvin S; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Zhang Y; Analytical Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Kristopeit A; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Ton C; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Winters MA; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Wagner JM; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Moore J; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA.
Source: Biotechnology and bioengineering [Biotechnol Bioeng] 2025 Aug; Vol. 122 (8), pp. 2082-2092. Date of Electronic Publication: 2025 May 14.
Publication Type: Journal Article
Journal Info: Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-0290
DOI:10.1002/bit.29028