CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin.
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| Title: | CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin. |
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| Authors: | Cahn JKB; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA., Ludwicki H; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Shingler J; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Gulvin S; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Zhang Y; Analytical Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Kristopeit A; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Ton C; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Winters MA; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Wagner JM; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA., Moore J; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA. |
| Source: | Biotechnology and bioengineering [Biotechnol Bioeng] 2025 Aug; Vol. 122 (8), pp. 2082-2092. Date of Electronic Publication: 2025 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 7502021 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0290 (Electronic) Linking ISSN: 00063592 NLM ISO Abbreviation: Biotechnol Bioeng Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40364716 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Cahn+JKB%22">Cahn JKB</searchLink>; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA.<br /><searchLink fieldCode="AU" term="%22Ludwicki+H%22">Ludwicki H</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Shingler+J%22">Shingler J</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Gulvin+S%22">Gulvin S</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Analytical Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Kristopeit+A%22">Kristopeit A</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Ton+C%22">Ton C</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Winters+MA%22">Winters MA</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Wagner+JM%22">Wagner JM</searchLink>; Process Research & Development, Merck & Co. Inc., West Point, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Moore+J%22">Moore J</searchLink>; Process Research & Development, Merck & Co. Inc., Rahway, New Jersey, USA. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%227502021%22">Biotechnology and bioengineering</searchLink> [Biotechnol Bioeng] 2025 Aug; Vol. 122 (8), pp. 2082-2092. <i>Date of Electronic Publication: </i>2025 May 14. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Wiley%22">Wiley </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>7502021 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-0290 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200063592%22">00063592 </searchLink><i>NLM ISO Abbreviation: </i>Biotechnol Bioeng <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40364716 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1002/bit.29028 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 2082 Titles: – TitleFull: CRISPR-Editing of the Vero Cell Line Improves Processability of Live Virus Vaccines by Enabling Targeted Proteolysis of Fibronectin. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Cahn JKB – PersonEntity: Name: NameFull: Ludwicki H – PersonEntity: Name: NameFull: Shingler J – PersonEntity: Name: NameFull: Gulvin S – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Kristopeit A – PersonEntity: Name: NameFull: Ton C – PersonEntity: Name: NameFull: Winters MA – PersonEntity: Name: NameFull: Wagner JM – PersonEntity: Name: NameFull: Moore J IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 08 Text: 2025 Aug Type: published Y: 2025 Identifiers: – Type: issn-electronic Value: 1097-0290 Numbering: – Type: volume Value: 122 – Type: issue Value: 8 Titles: – TitleFull: Biotechnology and bioengineering Type: main |
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