Discovery of a Novel [6-6-5-5-6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold.
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| Title: | Discovery of a Novel [6-6-5-5-6] Pentacyclic Tetrahydrocyclopentaphthalazinone as a Promising PARP Inhibitor Scaffold. |
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| Authors: | Doruk YU; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States., Diolaiti ME; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States., Ashworth A; UCSF Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, California 94158, United States.; Department of Medicine, University of California, San Francisco, California 94158, United States., Talele TT; Department of Pharmaceutical Sciences, College of Pharmacy and Health Sciences, St. John's University, Queens, New York 11439, United States. |
| Source: | ACS medicinal chemistry letters [ACS Med Chem Lett] 2025 Apr 03; Vol. 16 (5), pp. 776-783. Date of Electronic Publication: 2025 Apr 03 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 101521073 Publication Model: eCollection Cited Medium: Print ISSN: 1948-5875 (Print) Linking ISSN: 19485875 NLM ISO Abbreviation: ACS Med Chem Lett Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 1948-5875 |
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| DOI: | 10.1021/acsmedchemlett.4c00603 |
