Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione.
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| Title: | Quantitative Systems Toxicology Modeling of Acetaminophen Pharmacokinetics and Hepatic Biomarkers After Overdoses of Extended-Release and Immediate-Release Formulations in Adults With Chronic Alcohol Use or Low Glutathione. |
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| Authors: | Yang K; Quantitative Systems Pharmacology Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Beaudoin JJ; Quantitative Systems Pharmacology Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Howell BA; Quantitative Systems Pharmacology Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Mullin J; Physiologically-Based Pharmacokinetics Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Amini E; Physiologically-Based Pharmacokinetics Solutions, Simulations Plus Inc., Research Triangle Park, North Carolina, USA., Lai JCK; Kenvue, Summit, New Jersey, USA., Gelotte CK; Independent Consultant, Westbrook, Connecticut, USA., Sista S; Kenvue, Summit, New Jersey, USA., Atillasoy E; Kenvue, Summit, New Jersey, USA. |
| Source: | CPT: pharmacometrics & systems pharmacology [CPT Pharmacometrics Syst Pharmacol] 2025 Jul; Vol. 14 (7), pp. 1236-1251. Date of Electronic Publication: 2025 May 14. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Wiley Country of Publication: United States NLM ID: 101580011 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2163-8306 (Electronic) Linking ISSN: 21638306 NLM ISO Abbreviation: CPT Pharmacometrics Syst Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2163-8306 |
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| DOI: | 10.1002/psp4.70045 |
