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Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease.

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Title: Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease.
Authors: Singh M; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Louie RHY; School of Computer Science and Engineering, UNSW Sydney, Sydney, NSW 2052, Australia.; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia., Samir J; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia., Field MA; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; Australian Institute of Tropical Health and Medicine and Centre for Tropical Bioinformatics and Molecular Biology, James Cook University, Smithfield, QLD 4878, Australia., Milthorpe C; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia., Adikari T; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia., Mackie J; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Roper E; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia., Faulks M; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia., Jackson KJL; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia., Calcino A; Australian Institute of Tropical Health and Medicine and Centre for Tropical Bioinformatics and Molecular Biology, James Cook University, Smithfield, QLD 4878, Australia., Hardy MY; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia., Blombery P; Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC 3000, Australia.; University of Melbourne, Melbourne, VIC 3010, Australia., Amos TG; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia., Deveson IW; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Wende HV; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA., Floor SN; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA., Read SA; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia., Shek D; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia., Guerin A; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Ma CS; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Tangye SG; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Di Sabatino A; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy., Lenti MV; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy., Pasini A; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy., Ciccocioppo R; Gastroenterology Unit, Department of Medicine, University of Verona and AOUI Verona, Policlinico GB Rossi, Verona 37134, Italy., Ahlenstiel G; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia., Suan D; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia., Tye-Din JA; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Gastroenterology Department, Royal Melbourne Hospital, Parkville, VIC 3050, Australia., Goodnow CC; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; Cellular Genomics Futures Institute and School of Biomedical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia., Luciani F; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
Source: Science translational medicine [Sci Transl Med] 2025 May 14; Vol. 17 (798), pp. eadp6812. Date of Electronic Publication: 2025 May 14.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE
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  Data: Expanded T cell clones with lymphoma driver somatic mutations accumulate in refractory celiac disease.
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  Data: <searchLink fieldCode="AU" term="%22Singh+M%22">Singh M</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Louie+RHY%22">Louie RHY</searchLink>; School of Computer Science and Engineering, UNSW Sydney, Sydney, NSW 2052, Australia.; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Samir+J%22">Samir J</searchLink>; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Field+MA%22">Field MA</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; Australian Institute of Tropical Health and Medicine and Centre for Tropical Bioinformatics and Molecular Biology, James Cook University, Smithfield, QLD 4878, Australia.<br /><searchLink fieldCode="AU" term="%22Milthorpe+C%22">Milthorpe C</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Adikari+T%22">Adikari T</searchLink>; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Mackie+J%22">Mackie J</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Roper+E%22">Roper E</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Faulks+M%22">Faulks M</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Jackson+KJL%22">Jackson KJL</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Calcino+A%22">Calcino A</searchLink>; Australian Institute of Tropical Health and Medicine and Centre for Tropical Bioinformatics and Molecular Biology, James Cook University, Smithfield, QLD 4878, Australia.<br /><searchLink fieldCode="AU" term="%22Hardy+MY%22">Hardy MY</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Department of Medical Biology, University of Melbourne, Parkville, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Blombery+P%22">Blombery P</searchLink>; Peter MacCallum Cancer Centre and University of Melbourne, Melbourne, VIC 3000, Australia.; University of Melbourne, Melbourne, VIC 3010, Australia.<br /><searchLink fieldCode="AU" term="%22Amos+TG%22">Amos TG</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.<br /><searchLink fieldCode="AU" term="%22Deveson+IW%22">Deveson IW</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Wende+HV%22">Wende HV</searchLink>; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Floor+SN%22">Floor SN</searchLink>; Department of Cell and Tissue Biology, University of California, San Francisco, San Francisco, CA 94143, USA.<br /><searchLink fieldCode="AU" term="%22Read+SA%22">Read SA</searchLink>; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia.<br /><searchLink fieldCode="AU" term="%22Shek+D%22">Shek D</searchLink>; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia.<br /><searchLink fieldCode="AU" term="%22Guerin+A%22">Guerin A</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Ma+CS%22">Ma CS</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Tangye+SG%22">Tangye SG</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Di+Sabatino+A%22">Di Sabatino A</searchLink>; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy.<br /><searchLink fieldCode="AU" term="%22Lenti+MV%22">Lenti MV</searchLink>; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy.<br /><searchLink fieldCode="AU" term="%22Pasini+A%22">Pasini A</searchLink>; Department of Internal Medicine and Medical Therapeutics, University of Pavia, Pavia 27100, Italy.; First Department of Internal Medicine, Fondazione IRCCS Policlinico San Matteo, Pavia 27100, Italy.<br /><searchLink fieldCode="AU" term="%22Ciccocioppo+R%22">Ciccocioppo R</searchLink>; Gastroenterology Unit, Department of Medicine, University of Verona and AOUI Verona, Policlinico GB Rossi, Verona 37134, Italy.<br /><searchLink fieldCode="AU" term="%22Ahlenstiel+G%22">Ahlenstiel G</searchLink>; Westmead Institute for Medical Research, University of Sydney, Westmead, NSW 2145, Australia.; Blacktown Medical School, Western Sydney University, Blacktown, NSW 2148, Australia.; Blacktown Hospital, Blacktown, NSW 2148, Australia.<br /><searchLink fieldCode="AU" term="%22Suan+D%22">Suan D</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Clinical Medicine, Faculty of Medicine & Health, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Tye-Din+JA%22">Tye-Din JA</searchLink>; Walter and Eliza Hall Institute of Medical Research, Parkville, VIC 3052, Australia.; Gastroenterology Department, Royal Melbourne Hospital, Parkville, VIC 3050, Australia.<br /><searchLink fieldCode="AU" term="%22Goodnow+CC%22">Goodnow CC</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; Cellular Genomics Futures Institute and School of Biomedical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.<br /><searchLink fieldCode="AU" term="%22Luciani+F%22">Luciani F</searchLink>; Garvan Institute of Medical Research, Darlinghurst, NSW 2010, Australia.; School of Medical Sciences, UNSW Sydney, Sydney, NSW 2052, Australia.
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  Data: <searchLink fieldCode="JN" term="%22101505086%22">Science translational medicine</searchLink> [Sci Transl Med] 2025 May 14; Vol. 17 (798), pp. eadp6812. <i>Date of Electronic Publication: </i>2025 May 14.
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