Toxicarioside H induces ferroptosis in triple-negative breast cancer cells through Nrf2/HO-1 pathway.

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Title: Toxicarioside H induces ferroptosis in triple-negative breast cancer cells through Nrf2/HO-1 pathway.
Authors: Lin SP; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Huang FY; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Wu RH; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Xie WJ; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Chen MH; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Dai SZ; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China., Xu WT; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China. 459351866@qq.com., Zheng WP; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China. hnzwp2000@163.com., Tan GH; NHC Key Laboratory of Tropical Disease Control & The Second Affiliated Hospital, Hainan Medical University, 3 Xueyuan Road, Longhua District, Haikou City, 571199, Hainan Province, China. tanhoho@163.com.
Source: Discover oncology [Discov Oncol] 2025 May 15; Vol. 16 (1), pp. 772. Date of Electronic Publication: 2025 May 15.
Publication Type: Journal Article
Journal Info: Publisher: Springer Country of Publication: United States NLM ID: 101775142 Publication Model: Electronic Cited Medium: Internet ISSN: 2730-6011 (Electronic) Linking ISSN: 27306011 NLM ISO Abbreviation: Discov Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2730-6011
DOI:10.1007/s12672-025-02333-5