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Bryostatins 1 and 3 inhibit TRPM8 and modify TRPM8- and TRPV1-mediated lung epithelial cell responses to a proinflammatory stimulus via protein kinase C.

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Title:	Bryostatins 1 and 3 inhibit TRPM8 and modify TRPM8- and TRPV1-mediated lung epithelial cell responses to a proinflammatory stimulus via protein kinase C.
Authors:	Sun L; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Lamb JG; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Niu C; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah., Serna SN; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Romero EG; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Deering-Rice CE; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah., Golkowski M; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Reilly CA; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah. Electronic address: Chris.Reilly@pharm.utah.edu.
Source:	Molecular pharmacology [Mol Pharmacol] 2025 Jun; Vol. 107 (6), pp. 100042. Date of Electronic Publication: 2025 Apr 22.
Publication Type:	Journal Article
Journal Info:	Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	1521-0111
DOI:	10.1016/j.molpha.2025.100042