Bryostatins 1 and 3 inhibit TRPM8 and modify TRPM8- and TRPV1-mediated lung epithelial cell responses to a proinflammatory stimulus via protein kinase C.
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| Title: | Bryostatins 1 and 3 inhibit TRPM8 and modify TRPM8- and TRPV1-mediated lung epithelial cell responses to a proinflammatory stimulus via protein kinase C. |
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| Authors: | Sun L; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Lamb JG; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Niu C; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah., Serna SN; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah., Romero EG; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Deering-Rice CE; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah., Schmidt EW; Department of Medicinal Chemistry, University of Utah, Salt Lake City, Utah., Golkowski M; Department of Pharmacology and Toxicology, University of Utah, Salt Lake City, Utah; Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah., Reilly CA; Department of Pharmacology and Toxicology, Center for Human Toxicology, University of Utah, Salt Lake City, Utah. Electronic address: Chris.Reilly@pharm.utah.edu. |
| Source: | Molecular pharmacology [Mol Pharmacol] 2025 Jun; Vol. 107 (6), pp. 100042. Date of Electronic Publication: 2025 Apr 22. |
| Publication Type: | Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S. |
| Journal Info: | Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: Netherlands NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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