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FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors.

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Title: FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors.
Authors: Bastian K; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Orozco-Moreno M; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Thomas H; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK., Hodgson K; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Visser EA; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Rossing E; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Pijnenborg JFA; GlycoTherapeutics B.V, Nijmegen, the Netherlands., Eerden N; GlycoTherapeutics B.V, Nijmegen, the Netherlands., Wilson L; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK., Saravannan H; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Hanley O; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Grimsley G; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, USA., Frame F; Cancer Research Unit, Department of Biology, University of York, North Yorkshire, UK., Peng Z; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Knight B; NIHR Exeter Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., McCullagh P; Department of Pathology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., McGrath J; Exeter Surgical Health Services Research Unit, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK., Crundwell M; Institute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, Exeter, UK., Harries L; Institute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, Exeter, UK., Maitland NJ; Cancer Research Unit, Department of Biology, University of York, North Yorkshire, UK., Heer R; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK., Wang N; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK.; Leicester Cancer Research Centre, Department of Genetics, Genomics, and Cancer Sciences, University of Leicester, Leicester, UK., Goddard-Borger ED; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia., Guerrero RH; University of Zaragoza, Zaragoza, Spain.; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark., Boltje TJ; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands., Drake RR; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, USA., Scott E; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Elliott DJ; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK., Munkley J; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.
Source: Cancer medicine [Cancer Med] 2025 May; Vol. 14 (10), pp. e70959.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd Country of Publication: United States NLM ID: 101595310 Publication Model: Print Cited Medium: Internet ISSN: 2045-7634 (Electronic) Linking ISSN: 20457634 NLM ISO Abbreviation: Cancer Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: FUT8 Is a Critical Driver of Prostate Tumour Growth and Can Be Targeted Using Fucosylation Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Bastian+K%22">Bastian K</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Orozco-Moreno+M%22">Orozco-Moreno M</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Thomas+H%22">Thomas H</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Hodgson+K%22">Hodgson K</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Visser+EA%22">Visser EA</searchLink>; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Rossing+E%22">Rossing E</searchLink>; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Pijnenborg+JFA%22">Pijnenborg JFA</searchLink>; GlycoTherapeutics B.V, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Eerden+N%22">Eerden N</searchLink>; GlycoTherapeutics B.V, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Wilson+L%22">Wilson L</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Saravannan+H%22">Saravannan H</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Hanley+O%22">Hanley O</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Grimsley+G%22">Grimsley G</searchLink>; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Frame+F%22">Frame F</searchLink>; Cancer Research Unit, Department of Biology, University of York, North Yorkshire, UK.<br /><searchLink fieldCode="AU" term="%22Peng+Z%22">Peng Z</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Knight+B%22">Knight B</searchLink>; NIHR Exeter Clinical Research Facility, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22McCullagh+P%22">McCullagh P</searchLink>; Department of Pathology, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22McGrath+J%22">McGrath J</searchLink>; Exeter Surgical Health Services Research Unit, Royal Devon and Exeter NHS Foundation Trust, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Crundwell+M%22">Crundwell M</searchLink>; Institute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Harries+L%22">Harries L</searchLink>; Institute of Biomedical and Clinical Sciences, Medical School, College of Medicine and Health, University of Exeter, Exeter, UK.<br /><searchLink fieldCode="AU" term="%22Maitland+NJ%22">Maitland NJ</searchLink>; Cancer Research Unit, Department of Biology, University of York, North Yorkshire, UK.<br /><searchLink fieldCode="AU" term="%22Heer+R%22">Heer R</searchLink>; Newcastle University Centre for Cancer, Translational and Clinical Research Institute, Paul O'gorman Building, Newcastle University, Newcastle upon Tyne, UK.<br /><searchLink fieldCode="AU" term="%22Wang+N%22">Wang N</searchLink>; The Mellanby Centre for Musculoskeletal Research, Division of Clinical Medicine, The University of Sheffield, Sheffield, UK.; Leicester Cancer Research Centre, Department of Genetics, Genomics, and Cancer Sciences, University of Leicester, Leicester, UK.<br /><searchLink fieldCode="AU" term="%22Goddard-Borger+ED%22">Goddard-Borger ED</searchLink>; The Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria, Australia.; Department of Medical Biology, University of Melbourne, Parkville, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Guerrero+RH%22">Guerrero RH</searchLink>; University of Zaragoza, Zaragoza, Spain.; Copenhagen Center for Glycomics, Department of Cellular and Molecular Medicine, University of Copenhagen, Copenhagen, Denmark.<br /><searchLink fieldCode="AU" term="%22Boltje+TJ%22">Boltje TJ</searchLink>; Synthetic Organic Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, the Netherlands.<br /><searchLink fieldCode="AU" term="%22Drake+RR%22">Drake RR</searchLink>; Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, USA.<br /><searchLink fieldCode="AU" term="%22Scott+E%22">Scott E</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Elliott+DJ%22">Elliott DJ</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Munkley+J%22">Munkley J</searchLink>; Newcastle University Centre for Cancer, Newcastle University Institute of Biosciences, Newcastle, UK.
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