Factors associated with reaching maintenance therapy in patients with advanced biliary tract cancer treated with durvalumab: Real-world results from a multicenter and multinational study.

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Title: Factors associated with reaching maintenance therapy in patients with advanced biliary tract cancer treated with durvalumab: Real-world results from a multicenter and multinational study.
Authors: Rimini M; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Fornaro L; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy., Prinzi FL; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Rizzato MD; Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Saborowski A; Hannover Medical School, Hannover, Germany., Antonuzzo L; Clinical Oncology Unit, Careggi University Hospital; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy.; Department of Experimental and Clinical Medicine, University of Florence; Thoracic Surgery Unit, Careggi University Hospital, Florence, Italy., Rossari F; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Satake T; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Peeters F; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium., Vivaldi C; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Pressiani T; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy., Lucchetti J; Operative Research Unit of Medical Oncology, Fondazione Policlinico Universitario Campus Bio-Medico, Rome, Italy., Kim JW; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea., Abidoye O; Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA., Rapposelli IG; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Tamberi S; Medical Oncology, Santa Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy., Finkelmeier F; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany., Giordano G; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy., Pircher C; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Chon HJ; Division of Medical Oncology, Department of Internal Medicine, CHA Bundang Medical Center, CHA University School of Medicine, Seongnam, South Korea., Braconi C; University of Glasgow (School of Cancer Sciences), Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, Glasgow, UK., Qaisar A; University of Glasgow (School of Cancer Sciences), Beatson West of Scotland Cancer Centre, CRUK Scotland Centre, Glasgow, UK., Pirrone C; IRCCS Ospedale Policlinico San Martino, Medical Oncology Unit 1, Genoa, Italy., Castet F; Gastrointestinal and Endocrine Tumor Unit, Vall d'Hebron Institute of Oncology (VHIO), Hospital Universitari Vall d'Hebron, Vall d'Hebron Barcelona Hospital Campus, Barcelona, Spain., Tamburini E; Oncology Department and Palliative Care, Cardinale Panico Tricase City Hospital, Tricase, Italy., Yoo C; ASAN Medical Center, University of Ulsan College of Medicine, Seoul, South Korea., Parisi A; Clinica Oncologica e Centro Regionale di Genetica Oncologica, Università Politecnica delle Marche, Azienda Ospedaliero-Universitaria delle Marche, Ancona, Italy., Diana A; Oncology Unit, Ospedale del Mare, Naples, Italy., Scartozzi M; Medical Oncology, University and University Hospital, Cagliari, Italy., Prager GW; Department of Medicine I, Clinical Division of Oncology, Medical University Vienna, Austria., Avallone A; Clinical Experimental Abdominal Oncology Unit, Istituto Nazionale Tumori-IRCCS Fondazione G. Pascale, Naples, Italy., Schirripa M; Medical Oncology Unit, Department of Oncology and Hematology, Belcolle Hospital, Viterbo, Italy., Kim IH; Division of Oncology, Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea., Perkhofer L; Internal Medicine 1, University Hospital Ulm, Ulm, Germany.; Institute of Molecular Oncology and Stem Cell Biology, Ulm University Hospital, Ulm, Germany., Oneda E; Dipartimento di Oncologia medica, Fondazione Poliambulanza, Brescia, Italy., Verrico M; UOC Oncologia A, Department of Hematology, Oncology and Dermatology, Policlinico Umberto I University Hospital, Sapienza University of Rome, Rome, Italy., Couto N; Digestive Unit, Champalimaud Clinical Centre, Champalimaud Research Centre, Lisbon, Portugal., Adeva J; 12 de Octubre University Hospital, Spanish Society of Medical Oncology (SEOM), Madrid, Spain., Chan SL; State Key Laboratory of Translational Oncology, Department of Clinical Oncology, Sir YK Pao Centre for Cancer, Hong Kong Cancer Institute, Prince of Wales Hospital, The Chinese University of Hong Kong, Hong Kong., Spinelli GP; UOC Oncologia Territoriale, Polo Pontino, La Sapienza Università Di Roma, Latina, Italy., Personeni N; Medical Oncology Unit, P.O. Manerbio - ASST Garda, Manerbio (Brescia), Italy., Garajova I; Medical Oncology Unit, University Hospital of Parma, Parma, Italy., Rodriquenz MG; Oncology Unit, Fondazione IRCCS 'Casa Sollievo della Sofferenza', San Giovanni Rotondo, Italy., Leo S; Division of Oncology, Vito Fazzi Hospital, Lecce, Italy., Alvim CM; Medical Oncology Department, Hospital de Santa Maria, Centro Hospitalar Universitário Lisboa Norte, Lisbon, Portugal., Roque R; Portuguese Institute of Oncology of Coimbra, Coimbra, Portugal., Farinea G; 12 de Octubre University Hospital, Spanish Society of Medical Oncology (SEOM), Madrid, Spain., Salani F; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., De Rosa A; Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy.; Department of Surgery, Oncology and Gastroenterology, University of Padua, Padua, Italy., Lavacchi D; Clinical Oncology Unit, Careggi University Hospital; Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy., Camera S; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Ikeda M; Department of Hepatobiliary and Pancreatic Oncology, National Cancer Center Hospital East, Kashiwa, Japan., Dekervel J; Digestive Oncology, University Hospitals Leuven, Leuven, Belgium., Niger M; Department of Medical Oncology, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, Italy., Balsano R; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Tonini G; Department of Medicine and Surgery, Università Campus Bio-Medico di Roma, Rome, Italy., Corallo S; Medical Oncology Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy., Kang M; Division of Hematology/Medical Oncology, Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam-si, Gyeonggi-do, Republic of Korea., Bekaii-Saab T; Department of Internal Medicine, Mayo Clinic, Phoenix, Arizona, USA., Esposito L; Department of Medical Oncology, IRCCS Istituto Romagnolo per lo Studio dei Tumori (IRST) 'Dino Amadori', Meldola, Italy., Boccaccino A; Medical Oncology, Santa Maria delle Croci Hospital, AUSL Romagna, Ravenna, Italy., Vitiello F; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy., Himmelsbach V; Medical Clinic 1, Department of Gastroenterology, University Hospital Frankfurt, Frankfurt am Main, Germany., Landriscina M; Unit of Medical Oncology and Biomolecular Therapy, Policlinico Riuniti, Foggia, Italy.; Department of Medical and Surgical Sciences, University of Foggia, Foggia, Italy., Djaballah SA; Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Tesini G; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Masi G; Unit of Medical Oncology 2, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, Italy., Vogel A; Hannover Medical School, Hannover, Germany.; Longo Family Chair in Liver Cancer Research, Division of Gastroenterology and Hepatology, Toronto General Hospital, Medical Oncology, Princess Margaret Cancer Centre, Schwartz Reisman Liver Research Centre, Toronto, Canada., Lonardi S; Department of Oncology, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy., Rimassa L; Medical Oncology and Hematology Unit, Humanitas Cancer Center, IRCCS Humanitas Research Hospital, Rozzano (Milan), Italy.; Department of Biomedical Sciences, Humanitas University, Pieve Emanuele (Milan), Italy., Casadei-Gardini A; Department of Oncology, Vita-Salute San Raffaele University, IRCCS San Raffaele Scientific Institute Hospital, Milan, Italy.
Source: International journal of cancer [Int J Cancer] 2025 Sep 15; Vol. 157 (6), pp. 1246-1259. Date of Electronic Publication: 2025 May 19.
Publication Type: Journal Article; Multicenter Study
Journal Info: Publisher: Wiley-Liss Country of Publication: United States NLM ID: 0042124 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-0215 (Electronic) Linking ISSN: 00207136 NLM ISO Abbreviation: Int J Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-0215
DOI:10.1002/ijc.35481