Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP-CARE): A protocol for a randomized clinical trial.

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Title: Higher versus lower mean arterial blood pressure after cardiac arrest and resuscitation (MAP-CARE): A protocol for a randomized clinical trial.
Authors: Niemelä VH; Department of Anaesthesia and Intensive Care, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Reinikainen M; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Anaesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, Finland., Nielsen N; Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Lund University, Lund, Sweden.; Department of Anesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden., Bass F; The George Institute for Global Health, Sydney, Australia.; Royal North Shore Hospital, Sydney, Australia., Young P; Intensive Care Unit, Wellington Hospital, Wellington, New Zealand.; Medical Research Institute of New Zealand, Wellington, New Zealand.; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; Department of Critical Care, University of Melbourne, Melbourne, Victoria, Australia., Lilja G; Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden., Dankiewicz J; Department of Clinical Sciences Lund, Section of Cardiology, Skåne University Hospital, Lund, Sweden., Hammond N; Critical Care Program, The George Institute for Global Health, UNSW, Sydney, Australia.; Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Sydney, New South Wales, Australia., Hästbacka J; Wellbeing Services County of Pirkanmaa and Tampere University, Faculty of Medicine and Health Technology, Tampere University Hospital, Tampere, Finland., Levin H; Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Research, Development, Education and Innovation, Skåne University Hospital, Lund, Sweden., Moseby-Knappe M; Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Neurology and Rehabilitation, Skåne University Hospital, Lund, Sweden., Saxena M; Critical Care Division, Department of Intensive Care Medicine, The George Institute for Global Health, Sydney, Australia.; St George Hospital Clinical School, University of New South Wales, Sydney, New South Wales, Australia., Tiainen M; Department of Neurology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland., Ceric A; Anesthesia and Intensive Care, Department of Clinical Sciences, Lund University, Skane University Hospital, Malmö, Sweden., Holgersson J; Department of Clinical Sciences Lund, Anesthesia and Intensive Care, Lund University, Lund, Sweden.; Department of Anesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden., Kamp CB; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Copenhagen, Denmark., Tirkkonen J; Intensive Care Unit, Tampere University Hospital, Tampere, Finland., Oksanen T; Department of Anaesthesia and Intensive Care, Jorvi Hospital, University Hospital of Helsinki and University of Helsinki, Helsinki, Finland., Kaakinen T; Research Unit of Translational Medicine, Research Group of Anaesthesiology, Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland.; OYS Heart, Oulu University Hospital, MRC Oulu and University of Oulu, Oulu, Finland., Bendel S; Institute of Clinical Medicine, University of Eastern Finland, Kuopio, Finland.; Department of Anaesthesiology and Intensive Care, Kuopio University Hospital, Kuopio, Finland., Düring J; Department of Clinical Sciences, Anesthesia and Intensive Care, Lund University, Skåne University Hospital, Malmö, Sweden., Lybeck A; Anesthesia and Intensive Care, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden., Johnsson J; Department of Anesthesia and Intensive Care, Helsingborg Hospital, Helsingborg, Sweden., Unden J; Department of Operation and Intensive Care, Hallands Hospital Halmstad, Halmstad, Sweden.; Department of Intensive and Perioperative Care, Skåne University Hospital, Lund University, Lund, Sweden., Lundin A; Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden., Kåhlin J; Perioperative Medicine and Intensive Care (PMI), Karolinska University Hospital, Stockholm, Sweden.; Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm, Sweden., Grip J; Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden.; Department of Clinical Science, Intervention and Technology, Karolinska Institute, Stockholm, Sweden., Lotman E; North Estonia Medical Centre, Tallinn, Estonia., Romundstad L; Department of Anesthesia and Intensive Care Medicine, Division of Emergencies and Critical care, Oslo University Hospital, Oslo, Norway.; Lovisenberg Diaconal University College, Oslo, Norway., Seidel P; Department of Intensive Care Medicine, Stavanger University Hospital, Stavanger, Norway., Stammet P; Department of Anaesthesia and Intensive Care Medicine Centre, Hospitalier de Luxembourg, Luxembourg, Luxembourg.; Department of Life Sciences and Medicine, Faculty of Science, Technology and Medicine, University of Luxembourg, Esch-sur-Alzette, Luxembourg., Graf T; University Hospital Schleswig-Holstein, University Heart Center Lübeck, Lübeck, Germany.; German Center for Cardiovascular Research (DZHK), partner site Hamburg/Lübeck/Kiel, Germany., Mengel A; Department of Neurology and Stroke, University Hospital Tuebingen, Tuebingen, Germany.; Hertie Institute of Clinical Brain Research, Tuebingen, Germany., Leithner C; Department of Neurology, Freie Universität and Humboldt-Universität zu Berlin, Charité-Universitätsmedizin Berlin, Berlin, Germany., Nee J; Department of Nephrology and Medical Intensive Care, Charité-Universitaetsmedizin Berlin, Berlin, Germany., Druwé P; Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium., Ameloot K; Department of Cardiology, Ziekenhuis Oost-Limburg, Genk, Belgium., Wise MP; Adult Critical Care, University Hospital of Wales, Cardiff, UK., McGuigan PJ; Wellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.; Regional Intensive Care Unit, Royal Victoria Hospital, Belfast, UK., White J; CEDAR (Centre for Healthcare Evaluation, Device Assessment and Research), Cardiff and Vale University Health Board Cardiff, Cardiff, UK., Govier M; Bristol Royal Infirmary, University Hospitals Bristol and Weston, Bristol, UK., Maccaroni M; Essex Cardiothoracic Centre, Essex, UK.; Anglia Ruskin School of Medicine, ARU, Essex, UK., Ostermann M; Guy's & St Thomas' Hospital, London, UK., Hopkins P; Intensive Care Medicine Centre for Human & Applied Physiological Sciences, School of Basic & Medical Biosciences, Faculty of Life Sciences, Medicine King's College, London, UK.; Intensive Care Medicine, King's Critical Care, King's College Hospital, NHS Foundation Trust, London, UK., Proudfoot A; Department of Perioperative Medicine, Barts Heart Centre, St Bartholomew's Hospital, London, UK., Handslip R; St George's University Hospital NHS Foundation Trust, London, UK., Pogson D; Department of Critical Care, Portsmouth University Hospitals Trust Cosham, Portsmouth, UK., Jackson P; Leeds Teaching Hospitals NHS Trust, Leeds, UK., Nichol A; Australian and New Zealand Intensive Care Research Centre, Monash University, Melbourne, Victoria, Australia.; University College Dublin Clinical Research Centre at St Vincent's University Hospital, University College Dublin, Dublin, Ireland.; The Alfred Hospital, Melbourne, Australia., Haenggi M; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Hilty MP; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Iten M; Department of Intensive Care Medicine, Inselspital University Hospital Bern, Bern, Switzerland., Schrag C; Klinik für Intensivmedizin, Kantonsspital St. Gallen, St. Gallen, Switzerland., Nafi M; Istituto Cardiocentro Ticino, Lugano, Switzerland., Joannidis M; Division of Intensive Care and Emergency Medicine, Department of Internal Medicine, Medical University Insbruck, Innsbruck, Austria., Robba C; IRCCS Policlinico San Martino, Genoa, Italy.; Dipartimento di Scienze Chirurgiche Diagnostiche Integrate, University of Genova, Genova, Italy., Pellis T; Anaesthesia and Intensive Care, Pordenone Hospital Azienda Sanitaria Friuli Occidentale, Pordenone, Italy., Belohlavek J; 2nd Department of Internal Medicine, Cardiovascular Medicine, General University Hospital, 1st Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.; Institute for Heart Diseases, Wroclaw Medical University, Wrocław, Poland., Rob D; 2nd Department of Medicine, Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague, General University Hospital in Prague, Prague, Czech Republic., Arabi Y; King Saud bin Abdulaziz University for Health Sciences and King Abdullah International Medical Research Center, Riyadh, Saudi Arabia., Buabbas S; Department of Anesthesia, Critical Care and Pain Medicine, Jaber Alahmad Alsabah Hospital, Kuwait., Yew Woon C; Tan Tock Seng Hospital, Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore, Singapore., Aneman A; Intensive Care Unit, Liverpool Hospital, South Western Sydney Local Health District, Sydney, New South Wales, Australia.; South Western Clinical School, University of New South Wales, Sydney, New South Wales, Australia.; The Ingham Institute for Applied Medical Research, Sydney, New South Wales, Australia., Stewart A; Liverpool Hospital, Sydney, New South Wales, Australia., Arnott C; The George Institute for Global Health, Sydney, Australia., Ramanan M; Department of Cardiology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia.; Caboolture and Royal Brisbane and Women's Hospitals, Metro North Hospital and Health Service, Brisbane, Queensland, Australia.; School of Clinical Medicine, Queensland University of Technology, Brisbane, Queensland, Australia., Panwar R; Critical Care Division, The George Institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia.; School of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia., Delaney A; Critical Care Program, The George Institute for Global Health, UNSW, Sydney, Australia.; Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Sydney, New South Wales, Australia.; Intensive Care Unit, John Hunter Hospital, Newcastle, New South Wales, Australia., Reade M; Northern Clinical School, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia., Venkatesh B; The George Institute for Global Health, Sydney, Australia., Navarra L; Medical Research Institute of New Zealand, Wellington, New Zealand., Crichton B; Medical Research Institute of New Zealand, Wellington, New Zealand., Knight D; Department of Intensive Care, Christchurch Hospital, Christchurch, New Zealand., Williams A; Middlemore Hospital, Auckland, New Zealand., Friberg H; Anesthesia and Intensive Care, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Intensive and Perioperative Care, Skåne University Hospital, Malmö, Sweden., Cronberg T; Neurology, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Department of Neurology, Skåne University Hospital, Lund, Sweden., Jakobsen JC; Copenhagen Trial Unit, Centre for Clinical Intervention Research, Copenhagen University Hospital-Rigshospitalet, Copenhagen, Denmark.; Department of Regional Health Research, Faculty of Health Sciences, University of Southern Denmark, Copenhagen, Denmark., Skrifvars MB; Department of Anaesthesia and Intensive Care, Helsinki University Hospital and University of Helsinki, Helsinki, Finland.
Source: Acta anaesthesiologica Scandinavica [Acta Anaesthesiol Scand] 2025 Jul; Vol. 69 (6), pp. e70040.
Publication Type: Clinical Trial Protocol; Journal Article
Journal Info: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 0370270 Publication Model: Print Cited Medium: Internet ISSN: 1399-6576 (Electronic) Linking ISSN: 00015172 NLM ISO Abbreviation: Acta Anaesthesiol Scand Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1399-6576
DOI:10.1111/aas.70040