A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers.

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Title: A multiscale electro-metabolic model of a rat neocortical circuit reveals the impact of ageing on central cortical layers.
Authors: Farina S; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., Cattabiani A; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., Mandge D; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., Shichkova P; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland.; Biognosys AG, Schlieren, Switzerland., Isbister JB; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., Jacquemier J; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., King JG; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland., Markram H; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland.; Brain Mind Institute, École polytechnique fédérale de Lausanne (EPFL), Lausanne, Switzerland., Keller D; Blue Brain Project, École polytechnique fédérale de Lausanne (EPFL), Geneva, Switzerland.
Source: PLoS computational biology [PLoS Comput Biol] 2025 May 20; Vol. 21 (5), pp. e1013070. Date of Electronic Publication: 2025 May 20 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238922 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7358 (Electronic) Linking ISSN: 1553734X NLM ISO Abbreviation: PLoS Comput Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1553-7358
DOI:10.1371/journal.pcbi.1013070