Compounds with dual glutaminase inhibition and Nrf2 activation activities enhance morphine analgesia and reduce pain sensitization in chemotherapy-induced peripheral neuropathy mouse model.
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| Title: | Compounds with dual glutaminase inhibition and Nrf2 activation activities enhance morphine analgesia and reduce pain sensitization in chemotherapy-induced peripheral neuropathy mouse model. |
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| Authors: | Foster BK; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Kliebe V; Darby Children's Research Institute, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina., Elnaham HF; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Thompson MK; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Sagna SL; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Patton JS; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Brown SC; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana., Chen X; Department of Pharmaceutical and Clinical Sciences, College of Pharmacy and Health Sciences, Campbell University, Buies Creek, North Carolina., Liu T; Department of Biomedical Sciences, West Virginia School of Osteopathic Medicine, Lewisburg, West Virginia., Bowden J; Department of Pharmacology, College of Medicine, University of Arizona, Tuscon, Arizona., Streicher J; Department of Pharmacology, College of Medicine, University of Arizona, Tuscon, Arizona., Lei W; Department of Pharmaceutical and Graduate Life Sciences, College of Health Professions, Nursing & Pharmacy, Manchester University Fort Wayne, Fort Wayne, Indiana. Electronic address: wlei@manchester.edu. |
| Source: | The Journal of pharmacology and experimental therapeutics [J Pharmacol Exp Ther] 2025 Jun; Vol. 392 (6), pp. 103583. Date of Electronic Publication: 2025 Apr 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Country of Publication: Netherlands NLM ID: 0376362 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0103 (Electronic) Linking ISSN: 00223565 NLM ISO Abbreviation: J Pharmacol Exp Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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