Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency.
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| Title: | Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency. |
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| Authors: | Zhang X; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Huang L; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Department of Pharmacy, Shenzhen Clinical Research Center for Neurological Diseases, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China., Li C; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Department of Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China., Yang J; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Duan F; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Su Q; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Zhang Y; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China., Kou M; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Zhou X; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Guo L; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Chen S; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Niu Y; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Li Z; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Ou S; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China., Zhang M; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China., Cheng KK; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China., Wu J; Department of Pharmacy, Shenzhen Clinical Research Center for Neurological Diseases, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China., Xu X; State Key Laboratory of Trauma and Chemical Poisoning, Department of Stem Cell and Regenerative Medicine, Daping Hospital, Army Medical University, Chongqing, China., Lian Q; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China. qz.lian@siat.ac.cn.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. qz.lian@siat.ac.cn.; Center for Translational Stem Cell Biology, Hong Kong, and State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong SAR, China. qz.lian@siat.ac.cn. |
| Source: | Cell death discovery [Cell Death Discov] 2025 May 22; Vol. 11 (1), pp. 249. Date of Electronic Publication: 2025 May 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40399258 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Huang+L%22">Huang L</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Department of Pharmacy, Shenzhen Clinical Research Center for Neurological Diseases, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.; Department of Pain Medicine, Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Yang+J%22">Yang J</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Duan+F%22">Duan F</searchLink>; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Su+Q%22">Su Q</searchLink>; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Department of Emergency Medicine, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Kou+M%22">Kou M</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhou+X%22">Zhou X</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Guo+L%22">Guo L</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+S%22">Chen S</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Niu+Y%22">Niu Y</searchLink>; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Ou+S%22">Ou S</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Zhang+M%22">Zhang M</searchLink>; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Cheng+KK%22">Cheng KK</searchLink>; Department of Health Technology and Informatics, The Hong Kong Polytechnic University, Hong Kong SAR, China.<br /><searchLink fieldCode="AU" term="%22Wu+J%22">Wu J</searchLink>; Department of Pharmacy, Shenzhen Clinical Research Center for Neurological Diseases, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen, China.<br /><searchLink fieldCode="AU" term="%22Xu+X%22">Xu X</searchLink>; State Key Laboratory of Trauma and Chemical Poisoning, Department of Stem Cell and Regenerative Medicine, Daping Hospital, Army Medical University, Chongqing, China.<br /><searchLink fieldCode="AU" term="%22Lian+Q%22">Lian Q</searchLink>; Prenatal Diagnostic Center and Cord Blood Bank, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou, China. qz.lian@siat.ac.cn.; Faculty of Synthetic Biology, Shenzhen University of Advanced Technology; CAS Key Laboratory of Quantitative Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, China. qz.lian@siat.ac.cn.; Center for Translational Stem Cell Biology, Hong Kong, and State Key Laboratory of Pharmaceutical Biotechnology, The University of Hong Kong, Hong Kong SAR, China. qz.lian@siat.ac.cn. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2025 May 22; Vol. 11 (1), pp. 249. <i>Date of Electronic Publication: </i>2025 May 22. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=40399258 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41420-025-02524-7 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 249 Titles: – TitleFull: Gene therapy prevents onset of mitochondrial cardiomyopathy in neonatal mice with Ndufs6 deficiency. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Zhang X – PersonEntity: Name: NameFull: Huang L – PersonEntity: Name: NameFull: Li C – PersonEntity: Name: NameFull: Yang J – PersonEntity: Name: NameFull: Duan F – PersonEntity: Name: NameFull: Su Q – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Kou M – PersonEntity: Name: NameFull: Zhou X – PersonEntity: Name: NameFull: Guo L – PersonEntity: Name: NameFull: Chen S – PersonEntity: Name: NameFull: Niu Y – PersonEntity: Name: NameFull: Li Z – PersonEntity: Name: NameFull: Ou S – PersonEntity: Name: NameFull: Zhang M – PersonEntity: Name: NameFull: Cheng KK – PersonEntity: Name: NameFull: Wu J – PersonEntity: Name: NameFull: Xu X – PersonEntity: Name: NameFull: Lian Q IsPartOfRelationships: – BibEntity: Dates: – D: 22 M: 05 Text: 2025 May 22 Type: published Y: 2025 Identifiers: – Type: issn-print Value: 2058-7716 Numbering: – Type: volume Value: 11 – Type: issue Value: 1 Titles: – TitleFull: Cell death discovery Type: main |
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