Effects of 28-day simvastatin administration on emotional processing, reward learning, working memory, and salivary cortisol in healthy participants at-risk for depression: OxSTEP, an online experimental medicine trial.

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Title: Effects of 28-day simvastatin administration on emotional processing, reward learning, working memory, and salivary cortisol in healthy participants at-risk for depression: OxSTEP, an online experimental medicine trial.
Authors: De Giorgi R; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Waters S; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK., Gillespie AL; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Quinton AMG; Social, Genetic & Developmental Psychiatry Centre, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK., Colwell MJ; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Murphy SE; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Cowen PJ; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK., Harmer CJ; Department of Psychiatry, Warneford Hospital, University of Oxford, Oxford, UK.; Oxford Health NHS Foundation Trust, Warneford Hospital, Oxford, UK.
Source: Psychological medicine [Psychol Med] 2025 May 22; Vol. 55, pp. e155. Date of Electronic Publication: 2025 May 22.
Publication Type: Journal Article; Randomized Controlled Trial
Journal Info: Publisher: Cambridge University Press Country of Publication: England NLM ID: 1254142 Publication Model: Electronic Cited Medium: Internet ISSN: 1469-8978 (Electronic) Linking ISSN: 00332917 NLM ISO Abbreviation: Psychol Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1469-8978
DOI:10.1017/S0033291725001187