Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity.
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| Title: | Massively parallel reporter assays and mouse transgenic assays provide correlated and complementary information about neuronal enhancer activity. |
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| Authors: | Kosicki M; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Laboy Cintrón D; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, 94158, USA., Keukeleire P; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck, 23562, Lübeck, Germany., Schubach M; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany., Page NF; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, 94158, USA.; Department of Psychiatry and Behavioral Sciences, Kavli Institute for Fundamental Neuroscience, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA., Georgakopoulos-Soares I; Institute for Personalized Medicine, Department of Biochemistry and Molecular Biology, The Pennsylvania State University College of Medicine, Hershey, PA, 17033, USA., Akiyama JA; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Plajzer-Frick I; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Novak CS; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Kato M; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Hunter RD; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., von Maydell K; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Barton S; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Godfrey P; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Beckman E; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Sanders SJ; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, 94158, USA.; Department of Psychiatry and Behavioral Sciences, Kavli Institute for Fundamental Neuroscience, Weill Institute for Neurosciences, University of California, San Francisco, San Francisco, CA, USA.; Institute of Developmental and Regenerative Medicine, Department of Paediatrics, University of Oxford, Oxford, OX3 16 7TY, UK., Kircher M; Institute of Human Genetics, University Medical Center Schleswig-Holstein, University of Lübeck, 23562, Lübeck, Germany.; Berlin Institute of Health at Charité - Universitätsmedizin Berlin, 10117, Berlin, Germany., Pennacchio LA; Environmental Genomics & Systems Biology Division, Lawrence Berkeley National Laboratory, Berkeley, CA, 94720, USA., Ahituv N; Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA. nadav.ahituv@ucsf.edu.; Institute for Human Genetics, University of California San Francisco, San Francisco, CA, 94158, USA. nadav.ahituv@ucsf.edu. |
| Source: | Nature communications [Nat Commun] 2025 May 23; Vol. 16 (1), pp. 4786. Date of Electronic Publication: 2025 May 23. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2041-1723 |
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| DOI: | 10.1038/s41467-025-60064-1 |
