Novel pyrazole carboxylate derivatives as lonazolac bioisosteres with selective COX-2 inhibition: design, synthesis and anti-inflammatory activity.
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| Title: | Novel pyrazole carboxylate derivatives as lonazolac bioisosteres with selective COX-2 inhibition: design, synthesis and anti-inflammatory activity. |
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| Authors: | Fadaly WAA; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Elshewy A; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini Street, Cairo, 11562, Egypt.; Department of Natural and Applied Sciences, College of Arts and Sciences, The American University of Iraq-Baghdad (AUIB), Baghdad, Iraq., Abusabaa AHA; Department of Pharmaceutical Organic and Medicinal Chemistry, Faculty of Pharmacy, Fayoum University, Fayoum, 63514, Egypt., Amin DME; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Abdelhady HK; Physiology Department, Faculty of Medicine, Al-Azhar University, Assuit, Egypt., Haredy HH; Pharmacology Department, Faculty of Medicine, Al-Azhar University, Assuit, Egypt., Mahmoud AM; Biochemistery Department, Faculty of Science, Beni-Suef University, Beni-Suef, 62511, Egypt., Ibrahim NA; Medicinal Chemistry Department, Faculty of Pharmacy, Beni-Suef University, Beni-Suef, 62514, Egypt., Nemr MTM; Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Cairo University, Kasr El-Eini Street, Cairo, 11562, Egypt. Mohamed.nemr@pharma.cu.edu.eg. |
| Source: | Molecular diversity [Mol Divers] 2026 Feb; Vol. 30 (1), pp. 933-958. Date of Electronic Publication: 2025 May 22. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: ESCOM Science Publishers Country of Publication: Netherlands NLM ID: 9516534 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-501X (Electronic) Linking ISSN: 13811991 NLM ISO Abbreviation: Mol Divers Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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