Alveolar epithelial and vascular CXCR2 mediates transcytosis of CXCL1 in inflamed lungs.

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Title: Alveolar epithelial and vascular CXCR2 mediates transcytosis of CXCL1 in inflamed lungs.
Authors: Thomas K; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Rossaint J; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Ludwig N; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Mersmann S; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Kötting N; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Grenzheuser J; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Schemmelmann L; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Oguama M; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Margraf A; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Block H; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Henke K; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Hellenthal K; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany., Mirakaj V; Department of Anaesthesiology and Intensive Care Medicine, University Tübingen, Tübingen, Germany., Gerke V; Institute of Medical Biochemistry, Centre for Molecular Biology of Inflammation (ZMBE), University of Münster, Münster, Germany., Hansen U; Institute of Experimental Musculoskeletal Medicine, University Hospital Münster, Münster, Germany., Gäher K; Institute of Experimental Musculoskeletal Medicine, University Hospital Münster, Münster, Germany., Engelhardt M; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany., Roth J; Institute of Immunology, University Hospital Münster, Münster, Germany., Eble J; Institute of Physiological Chemistry and Pathobiochemistry, University of Münster, Münster, Germany., Hub E; Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Rot A; Centre for Microvascular Research, William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, London, UK., Alon R; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Zarbock A; Department of Anesthesiology, Intensive Care and Pain Medicine, University Hospital Münster, Münster, Germany. zarbock@uni-muenster.de.
Source: Nature communications [Nat Commun] 2025 May 24; Vol. 16 (1), pp. 4846. Date of Electronic Publication: 2025 May 24.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60174-w