Therapeutic implications of synonymous gene recoding: insights into mechanisms controlling protein biogenesis and activity.

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Title: Therapeutic implications of synonymous gene recoding: insights into mechanisms controlling protein biogenesis and activity.
Authors: Lin BC; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Jankowska KI; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Katneni UK; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Amarasinghe R; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Padhiar N; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Hamasaki-Katagiri N; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Wu WW; Facility for Biotechnology Resources, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Zhu H; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan., Taguchi H; Cell Biology Center, Institute of Innovative Research, Tokyo Institute of Technology, Yokohama, 226-8503, Japan., Ghosh A; Center for Gene Regulation in Health and Disease and the Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, OH, 44115, United States., Holcomb DD; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Phue JN; Facility for Biotechnology Resources, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Fumagalli SE; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Freedberg DI; Laboratory of Bacterial Polysaccharides, Division of Bacterial, Parasitic, and Allergenic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Kimchi O; Center for the Physics of Biological Function, Princeton University, Princeton, NJ, 08544, United States., Shen RF; Facility for Biotechnology Resources, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Komar AA; Center for Gene Regulation in Health and Disease and the Department of Biological, Geological and Environmental Sciences, Cleveland State University, Cleveland, OH, 44115, United States., Sauna ZE; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States., Kimchi-Sarfaty C; Division of Hemostasis, Office of Therapeutic Products, Center for Biologics Evaluation and Research, US FDA, Silver Spring, MD, 20993, United States.
Source: Protein & cell [Protein Cell] 2025 Oct 31; Vol. 16 (10), pp. 905-910.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: Germany NLM ID: 101532368 Publication Model: Print Cited Medium: Internet ISSN: 1674-8018 (Electronic) Linking ISSN: 1674800X NLM ISO Abbreviation: Protein Cell Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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ISSN:1674-8018
DOI:10.1093/procel/pwaf028