Kaurenoic acid is a potent inhibitor of SARS-CoV-2 RNA synthesis, virion assembly, and release in vitro.

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Title: Kaurenoic acid is a potent inhibitor of SARS-CoV-2 RNA synthesis, virion assembly, and release in vitro.
Authors: Santos IA; Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.; Faculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom., Grosche VR; Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.; Faculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.; Institute of Biosciences, Humanities and Exact Sciences, São Paulo State University, São Jose do Rio Preto, Brazil., Cassani NM; Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.; Faculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom., Veneziani RCS; Nucleus of Research in Sciences and Technology, University of Franca, Franca, Brazil., Ribeiro GL; Nucleus of Research in Sciences and Technology, University of Franca, Franca, Brazil., Bastos JK; Faculty of Pharmaceutical Sciences of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil., Nicolau-Junior N; Institute of Biotechnology, Federal University of Uberlândia (UFU), Uberlândia, Brazil., Merits A; Institute of Bioengineering, University of Tartu, Tartu, Estonia., Martins CHG; Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil., Harris M; Faculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom., Jardim ACG; Institute of Biomedical Sciences, Federal University of Uberlândia, Uberlândia, Brazil.; Faculty of Biological Sciences, School of Molecular and Cellular Biology, University of Leeds, Leeds, United Kingdom.
Source: Frontiers in microbiology [Front Microbiol] 2025 May 09; Vol. 16, pp. 1540934. Date of Electronic Publication: 2025 May 09 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1664-302X
DOI:10.3389/fmicb.2025.1540934