No overshoot of bone turnover after withdrawal of denosumab treatment of adults with Langerhans cell histiocytosis: a prospective clinical trial.

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Title: No overshoot of bone turnover after withdrawal of denosumab treatment of adults with Langerhans cell histiocytosis: a prospective clinical trial.
Authors: Makras P; Department of Medical Research, 251 Hellenic Air Force & VA General Hospital, 3 Kanellopoulou Str, Athens, Greece. pmakras@gmail.com.; Department of Medical Research, LCH Adult Clinic, 251 Hellenic Air Force & VA General Hospital, 3 Kanellopoulou Str, 11525, Athens, Greece. pmakras@gmail.com., Yavropoulou MP; Department of Medical Research, LCH Adult Clinic, 251 Hellenic Air Force & VA General Hospital, 3 Kanellopoulou Str, 11525, Athens, Greece.; Εndocrinology Unit, First Department of Propaedeutic and Internal Medicine, National and Kapodistrian University of Athens, Medical School, 11527, Athens, Greece., Anastasilakis AD; Department of Endocrinology, 424 General Military Hospital, Thessaloniki, Greece., Papatheodorou A; Department of Medical Research, 251 Hellenic Air Force & VA General Hospital, 3 Kanellopoulou Str, Athens, Greece., Papapoulos SE; Department of Medical Research, 251 Hellenic Air Force & VA General Hospital, 3 Kanellopoulou Str, Athens, Greece.; Center for Bone Quality, Department of Internal Medicine, Section Endocrinology, Leiden University Medical Center, Leiden, The Netherlands.
Source: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA [Osteoporos Int] 2025 Jul; Vol. 36 (7), pp. 1231-1237. Date of Electronic Publication: 2025 May 26.
Publication Type: Journal Article; Clinical Trial, Phase II
Journal Info: Publisher: Springer International Country of Publication: England NLM ID: 9100105 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1433-2965 (Electronic) Linking ISSN: 0937941X NLM ISO Abbreviation: Osteoporos Int Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1433-2965
DOI:10.1007/s00198-025-07538-6