Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations.

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Title: Development and Validation of Polygenic Risk Scores for Blood Pressure Traits in Continental African Populations.
Authors: Onyenobi E; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore., Zhong M; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore., Soremekun O; The African Computational Genomics Research Group, Medical Research Council/Uganda Virus Research Institute, and London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Entebbe, Uganda (O.S., A.K., S.F.)., Kamiza A; The African Computational Genomics Research Group, Medical Research Council/Uganda Virus Research Institute, and London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Entebbe, Uganda (O.S., A.K., S.F.)., Boua R; Clinical Research Unit of Nanoro, Institut de Recherche en Sciences de la Santé, Nanoro, Burkina Faso (R.B.).; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences (R.B., A.C., S.H., M.R.), University of the Witwatersrand, Johannesburg, South Africa., Chikowore T; Department of Medicine, Harvard Medical School, Boston, MA (T.C.).; Channing Division of Network Medicine, Brigham and Women's Hospital, Boston, MA (T.C.)., Fatumo S; The African Computational Genomics Research Group, Medical Research Council/Uganda Virus Research Institute, and London School of Hygiene and Tropical Medicine (MRC/UVRI & LSHTM), Entebbe, Uganda (O.S., A.K., S.F.).; Precision Healthcare University Research Institute, Queen Mary University of London, United Kingdom (S.F.)., Choudhury A; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences (R.B., A.C., S.H., M.R.), University of the Witwatersrand, Johannesburg, South Africa., Hazelhurst S; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences (R.B., A.C., S.H., M.R.), University of the Witwatersrand, Johannesburg, South Africa.; School of Electrical and Information Engineering (S.H.), University of the Witwatersrand, Johannesburg, South Africa., Adebamowo C; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore.; Greenebaum Comprehensive Cancer Center (C.A., S.N.A.), University of Maryland School of Medicine, Baltimore., Ramsay M; Sydney Brenner Institute for Molecular Bioscience, Faculty of Health Sciences (R.B., A.C., S.H., M.R.), University of the Witwatersrand, Johannesburg, South Africa., Tayo B; Department of Public Health Sciences, Loyola University Parkinson School of Health Sciences and Public Health, Maywood, IL (B.T.)., Albrecht JS; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore., O'Connor TD; Department of Medicine (T.D.O., B.D.M.), University of Maryland School of Medicine, Baltimore., Zhang Y; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore., Mitchell BD; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore.; Department of Medicine (T.D.O., B.D.M.), University of Maryland School of Medicine, Baltimore., Adebamowo SN; Department of Epidemiology and Public Health (E.O., M.Z., C.A., J.S.A., Y.Z., B.D.M., S.N.A.), University of Maryland School of Medicine, Baltimore.; Greenebaum Comprehensive Cancer Center (C.A., S.N.A.), University of Maryland School of Medicine, Baltimore.
Corporate Authors: ACCME Research Group
Source: Circulation. Genomic and precision medicine [Circ Genom Precis Med] 2025 Jun; Vol. 18 (3), pp. e005048. Date of Electronic Publication: 2025 May 27.
Publication Type: Journal Article
Journal Info: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 101714113 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2574-8300 (Electronic) Linking ISSN: 25748300 NLM ISO Abbreviation: Circ Genom Precis Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2574-8300
DOI:10.1161/CIRCGEN.124.005048