A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway.
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| Title: | A Novel Flavonoid Derivative of Icariside II (YS-10) Improves Erectile Dysfunction in a Diabetic Rat Model by Inhibiting Ferroptosis via Activation of the Nrf2/HO-1/GPX4 Pathway. |
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| Authors: | Liu Y; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Liu GN; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Zha YR; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Pan CL; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Xu YD; Department of Urology, Beijing Friendship Hospital, Capital Medical University, Beijing, 100050, People's Republic of China., Li HW; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Zang YY; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Wang WQ; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Yao JJ; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Sun JT; Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China.; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Yang Y; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China., Wei ZT; Department of Urology, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, People's Republic of China. |
| Source: | Drug design, development and therapy [Drug Des Devel Ther] 2025 May 28; Vol. 19, pp. 4481-4500. Date of Electronic Publication: 2025 May 28 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Dove Press Limited Country of Publication: New Zealand NLM ID: 101475745 Publication Model: eCollection Cited Medium: Internet ISSN: 1177-8881 (Electronic) Linking ISSN: 11778881 NLM ISO Abbreviation: Drug Des Devel Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1177-8881 |
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| DOI: | 10.2147/DDDT.S518992 |
