A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial.
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| Title: | A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial. |
|---|---|
| Authors: | Zane LK; NCI, Rockville, Maryland., Yee LM; NCI, Rockville, Maryland., Chang TC; Frederick National Laboratory for Cancer Research, Frederick, Maryland., Sklar J; Yale University, New Haven, Connecticut., Yang G; Yale University, New Haven, Connecticut., Wen JD; Yale University, New Haven, Connecticut., Li P; Yale University, New Haven, Connecticut., Harrington R; Frederick National Laboratory for Cancer Research, Frederick, Maryland., Sims DJ; Frederick National Laboratory for Cancer Research, Frederick, Maryland., Harper K; Frederick National Laboratory for Cancer Research, Frederick, Maryland., Trent JM; Ashion Analytics, LLC, Phoenix, Arizona., LoBello JR; Ashion Analytics, LLC, Phoenix, Arizona., Szelinger S; Ashion Analytics, LLC, Phoenix, Arizona., Benson K; Caris Life Sciences, Irving, Texas., Zeng J; Caris Life Sciences, Irving, Texas., Poorman K; Caris Life Sciences, Irving, Texas., Xu D; CellNetix Pathology and Laboratories, Tukwila, Washington., Frampton GM; Foundation Medicine, Inc., Boston, Massachusetts., Pavlick DC; Foundation Medicine, Inc., Boston, Massachusetts., Miller VA; Foundation Medicine, Inc., Boston, Massachusetts., Tandon B; GenPath (BioReference Laboratories, Inc.), Elmwood Park, New Jersey., Swat W; GenPath (BioReference Laboratories, Inc.), Elmwood Park, New Jersey., Weiss L; NeoGenomics Laboratories, Inc., Fort Myers, Florida., Funari VA; NeoGenomics Laboratories, Inc., Fort Myers, Florida., Conroy JM; OmniSeq, Buffalo, New York., Prescott JL; PathGroup, Brentwood, Tennessee., Chandra PK; PathGroup, Brentwood, Tennessee., Ma C; Quest Diagnostics Inc., Secaucus, New Jersey., Champion KJ; Quest Diagnostics Inc., Secaucus, New Jersey., Baschkopf GX; Quest Diagnostics Inc., Secaucus, New Jersey., Fesko YA; Quest Diagnostics Inc., Secaucus, New Jersey., Freitas TAK; Quest Diagnostics Inc., Secaucus, New Jersey., Tomlins SA; Strata Oncology, Inc., Ann Arbor, Michigan., Hovelson DH; Strata Oncology, Inc., Ann Arbor, Michigan., White K; Tempus AI, Inc., Chicago, Illinois., Sorrells S; Tempus AI, Inc., Chicago, Illinois., Tell R; Tempus AI, Inc., Chicago, Illinois., Beaubier N; Tempus AI, Inc., Chicago, Illinois., King D; Tempus AI, Inc., Chicago, Illinois., Li L; The Jackson Laboratory, Bar Harbor, Maine., Kelly K; The Jackson Laboratory, Bar Harbor, Maine., Uvalic J; The Jackson Laboratory, Bar Harbor, Maine., Meyers B; The Jackson Laboratory, Bar Harbor, Maine., Kolhe R; Georgia Esoteric & Molecular Diagnostic Laboratory, Augusta University, Augusta, Georgia., Lindeman NI; The Brigham and Women's Hospital Center for Advanced Molecular Diagnostics, Boston, Massachusetts., Baltay M; The Brigham and Women's Hospital Center for Advanced Molecular Diagnostics, Boston, Massachusetts., Sholl LM; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California., Lopategui J; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California., Vail E; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California., Zhang W; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California., Telatar M; Clinical Molecular Diagnostics Laboratory, City of Hope National Medical Center, Duarte, California., Afkhami M; Clinical Molecular Diagnostics Laboratory, City of Hope National Medical Center, Duarte, California., Hsiao SJ; Department of Pathology and Cell Biology, Laboratory of Personalized Genomic Medicine, Columbia University, New York, New York., Mansukhani MM; Department of Pathology and Cell Biology, Laboratory of Personalized Genomic Medicine, Columbia University, New York, New York., Adams E; Johns Hopkins Genomics, Baltimore, Maryland., Jiang L; Johns Hopkins Genomics, Baltimore, Maryland., Aldape KD; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland., Raffeld M; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland., Xi L; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland., Stehr H; Molecular Genetic Pathology Laboratory, Stanford Health Care, Stanford, California., Segal JP; Clinical Genomics Laboratory, The University of Chicago, Chicago, Illinois., Aisner DL; Colorado Molecular Correlates Laboratory, The University of Colorado, Boulder, Colorado., Davies KD; Colorado Molecular Correlates Laboratory, The University of Colorado, Boulder, Colorado., Brown NA; Michigan Medicine Molecular Diagnostics Laboratory, The University of Michigan, Ann Arbor, Michigan., Livingston RJ; Genetics and Solid Tumor Laboratory, The University of Washington, Seattle, Washington., Konnick EQ; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York., Song W; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York., Solomon JP; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York., Walther Z; Yale Tumor Profiling Laboratory, Yale University, New Haven, Connecticut., McShane LM; NCI, Rockville, Maryland., Harris LN; NCI, Rockville, Maryland., Chen AP; NCI, Rockville, Maryland., Tsongalis GJ; Dartmouth Health System, The Dartmouth Cancer Center and Geisel School of Medicine, Lebanon, New Hampshire., Hamilton SR; MD Anderson Cancer Center, Houston, Texas., Flaherty KT; Harvard Medical School, Boston, Massachusetts., O'Dwyer PJ; University of Pennsylvania, Philadelphia, Pennsylvania., Conley BA; NCI, Rockville, Maryland., Patton DR; NCI, Rockville, Maryland., Iafrate AJ; Massachusetts General Hospital, Boston, Massachusetts., Williams PM; Frederick National Laboratory for Cancer Research, Frederick, Maryland., Tricoli JV; NCI, Rockville, Maryland., Karlovich C; Frederick National Laboratory for Cancer Research, Frederick, Maryland. |
| Corporate Authors: | NCI-MATCH Designated Laboratories, for NCI-COMPASS Team, for NCI-MATCH Designated Laboratories |
| Source: | Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2025 Aug 14; Vol. 31 (16), pp. 3512-3525. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 40465838 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: A Concordance Study among 26 NGS Laboratories Participating in the NCI Molecular Analysis for Therapy Choice Clinical Trial. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Zane+LK%22">Zane LK</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Yee+LM%22">Yee LM</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Chang+TC%22">Chang TC</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Sklar+J%22">Sklar J</searchLink>; Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Yang+G%22">Yang G</searchLink>; Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Wen+JD%22">Wen JD</searchLink>; Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Li+P%22">Li P</searchLink>; Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22Harrington+R%22">Harrington R</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Sims+DJ%22">Sims DJ</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Harper+K%22">Harper K</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Trent+JM%22">Trent JM</searchLink>; Ashion Analytics, LLC, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22LoBello+JR%22">LoBello JR</searchLink>; Ashion Analytics, LLC, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Szelinger+S%22">Szelinger S</searchLink>; Ashion Analytics, LLC, Phoenix, Arizona.<br /><searchLink fieldCode="AU" term="%22Benson+K%22">Benson K</searchLink>; Caris Life Sciences, Irving, Texas.<br /><searchLink fieldCode="AU" term="%22Zeng+J%22">Zeng J</searchLink>; Caris Life Sciences, Irving, Texas.<br /><searchLink fieldCode="AU" term="%22Poorman+K%22">Poorman K</searchLink>; Caris Life Sciences, Irving, Texas.<br /><searchLink fieldCode="AU" term="%22Xu+D%22">Xu D</searchLink>; CellNetix Pathology and Laboratories, Tukwila, Washington.<br /><searchLink fieldCode="AU" term="%22Frampton+GM%22">Frampton GM</searchLink>; Foundation Medicine, Inc., Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Pavlick+DC%22">Pavlick DC</searchLink>; Foundation Medicine, Inc., Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Miller+VA%22">Miller VA</searchLink>; Foundation Medicine, Inc., Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Tandon+B%22">Tandon B</searchLink>; GenPath (BioReference Laboratories, Inc.), Elmwood Park, New Jersey.<br /><searchLink fieldCode="AU" term="%22Swat+W%22">Swat W</searchLink>; GenPath (BioReference Laboratories, Inc.), Elmwood Park, New Jersey.<br /><searchLink fieldCode="AU" term="%22Weiss+L%22">Weiss L</searchLink>; NeoGenomics Laboratories, Inc., Fort Myers, Florida.<br /><searchLink fieldCode="AU" term="%22Funari+VA%22">Funari VA</searchLink>; NeoGenomics Laboratories, Inc., Fort Myers, Florida.<br /><searchLink fieldCode="AU" term="%22Conroy+JM%22">Conroy JM</searchLink>; OmniSeq, Buffalo, New York.<br /><searchLink fieldCode="AU" term="%22Prescott+JL%22">Prescott JL</searchLink>; PathGroup, Brentwood, Tennessee.<br /><searchLink fieldCode="AU" term="%22Chandra+PK%22">Chandra PK</searchLink>; PathGroup, Brentwood, Tennessee.<br /><searchLink fieldCode="AU" term="%22Ma+C%22">Ma C</searchLink>; Quest Diagnostics Inc., Secaucus, New Jersey.<br /><searchLink fieldCode="AU" term="%22Champion+KJ%22">Champion KJ</searchLink>; Quest Diagnostics Inc., Secaucus, New Jersey.<br /><searchLink fieldCode="AU" term="%22Baschkopf+GX%22">Baschkopf GX</searchLink>; Quest Diagnostics Inc., Secaucus, New Jersey.<br /><searchLink fieldCode="AU" term="%22Fesko+YA%22">Fesko YA</searchLink>; Quest Diagnostics Inc., Secaucus, New Jersey.<br /><searchLink fieldCode="AU" term="%22Freitas+TAK%22">Freitas TAK</searchLink>; Quest Diagnostics Inc., Secaucus, New Jersey.<br /><searchLink fieldCode="AU" term="%22Tomlins+SA%22">Tomlins SA</searchLink>; Strata Oncology, Inc., Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Hovelson+DH%22">Hovelson DH</searchLink>; Strata Oncology, Inc., Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22White+K%22">White K</searchLink>; Tempus AI, Inc., Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Sorrells+S%22">Sorrells S</searchLink>; Tempus AI, Inc., Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Tell+R%22">Tell R</searchLink>; Tempus AI, Inc., Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Beaubier+N%22">Beaubier N</searchLink>; Tempus AI, Inc., Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22King+D%22">King D</searchLink>; Tempus AI, Inc., Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Li+L%22">Li L</searchLink>; The Jackson Laboratory, Bar Harbor, Maine.<br /><searchLink fieldCode="AU" term="%22Kelly+K%22">Kelly K</searchLink>; The Jackson Laboratory, Bar Harbor, Maine.<br /><searchLink fieldCode="AU" term="%22Uvalic+J%22">Uvalic J</searchLink>; The Jackson Laboratory, Bar Harbor, Maine.<br /><searchLink fieldCode="AU" term="%22Meyers+B%22">Meyers B</searchLink>; The Jackson Laboratory, Bar Harbor, Maine.<br /><searchLink fieldCode="AU" term="%22Kolhe+R%22">Kolhe R</searchLink>; Georgia Esoteric & Molecular Diagnostic Laboratory, Augusta University, Augusta, Georgia.<br /><searchLink fieldCode="AU" term="%22Lindeman+NI%22">Lindeman NI</searchLink>; The Brigham and Women's Hospital Center for Advanced Molecular Diagnostics, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Baltay+M%22">Baltay M</searchLink>; The Brigham and Women's Hospital Center for Advanced Molecular Diagnostics, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Sholl+LM%22">Sholl LM</searchLink>; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Lopategui+J%22">Lopategui J</searchLink>; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Vail+E%22">Vail E</searchLink>; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Zhang+W%22">Zhang W</searchLink>; Molecular Pathology Laboratory, Cedars-Sinai Medical Center, Los Angeles, California.<br /><searchLink fieldCode="AU" term="%22Telatar+M%22">Telatar M</searchLink>; Clinical Molecular Diagnostics Laboratory, City of Hope National Medical Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Afkhami+M%22">Afkhami M</searchLink>; Clinical Molecular Diagnostics Laboratory, City of Hope National Medical Center, Duarte, California.<br /><searchLink fieldCode="AU" term="%22Hsiao+SJ%22">Hsiao SJ</searchLink>; Department of Pathology and Cell Biology, Laboratory of Personalized Genomic Medicine, Columbia University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Mansukhani+MM%22">Mansukhani MM</searchLink>; Department of Pathology and Cell Biology, Laboratory of Personalized Genomic Medicine, Columbia University, New York, New York.<br /><searchLink fieldCode="AU" term="%22Adams+E%22">Adams E</searchLink>; Johns Hopkins Genomics, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Jiang+L%22">Jiang L</searchLink>; Johns Hopkins Genomics, Baltimore, Maryland.<br /><searchLink fieldCode="AU" term="%22Aldape+KD%22">Aldape KD</searchLink>; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Raffeld+M%22">Raffeld M</searchLink>; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Xi+L%22">Xi L</searchLink>; Laboratory of Pathology, Center for Cancer Research, NCI, Bethesda, Maryland.<br /><searchLink fieldCode="AU" term="%22Stehr+H%22">Stehr H</searchLink>; Molecular Genetic Pathology Laboratory, Stanford Health Care, Stanford, California.<br /><searchLink fieldCode="AU" term="%22Segal+JP%22">Segal JP</searchLink>; Clinical Genomics Laboratory, The University of Chicago, Chicago, Illinois.<br /><searchLink fieldCode="AU" term="%22Aisner+DL%22">Aisner DL</searchLink>; Colorado Molecular Correlates Laboratory, The University of Colorado, Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Davies+KD%22">Davies KD</searchLink>; Colorado Molecular Correlates Laboratory, The University of Colorado, Boulder, Colorado.<br /><searchLink fieldCode="AU" term="%22Brown+NA%22">Brown NA</searchLink>; Michigan Medicine Molecular Diagnostics Laboratory, The University of Michigan, Ann Arbor, Michigan.<br /><searchLink fieldCode="AU" term="%22Livingston+RJ%22">Livingston RJ</searchLink>; Genetics and Solid Tumor Laboratory, The University of Washington, Seattle, Washington.<br /><searchLink fieldCode="AU" term="%22Konnick+EQ%22">Konnick EQ</searchLink>; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Song+W%22">Song W</searchLink>; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Solomon+JP%22">Solomon JP</searchLink>; Clinical Genomics Laboratory, Weill Cornell Medicine, New York, New York.<br /><searchLink fieldCode="AU" term="%22Walther+Z%22">Walther Z</searchLink>; Yale Tumor Profiling Laboratory, Yale University, New Haven, Connecticut.<br /><searchLink fieldCode="AU" term="%22McShane+LM%22">McShane LM</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Harris+LN%22">Harris LN</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Chen+AP%22">Chen AP</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Tsongalis+GJ%22">Tsongalis GJ</searchLink>; Dartmouth Health System, The Dartmouth Cancer Center and Geisel School of Medicine, Lebanon, New Hampshire.<br /><searchLink fieldCode="AU" term="%22Hamilton+SR%22">Hamilton SR</searchLink>; MD Anderson Cancer Center, Houston, Texas.<br /><searchLink fieldCode="AU" term="%22Flaherty+KT%22">Flaherty KT</searchLink>; Harvard Medical School, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22O'Dwyer+PJ%22">O'Dwyer PJ</searchLink>; University of Pennsylvania, Philadelphia, Pennsylvania.<br /><searchLink fieldCode="AU" term="%22Conley+BA%22">Conley BA</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Patton+DR%22">Patton DR</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Iafrate+AJ%22">Iafrate AJ</searchLink>; Massachusetts General Hospital, Boston, Massachusetts.<br /><searchLink fieldCode="AU" term="%22Williams+PM%22">Williams PM</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland.<br /><searchLink fieldCode="AU" term="%22Tricoli+JV%22">Tricoli JV</searchLink>; NCI, Rockville, Maryland.<br /><searchLink fieldCode="AU" term="%22Karlovich+C%22">Karlovich C</searchLink>; Frederick National Laboratory for Cancer Research, Frederick, Maryland. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22NCI-MATCH+Designated+Laboratories%22">NCI-MATCH Designated Laboratories</searchLink><br /><searchLink fieldCode="CA" term="%22for+NCI-COMPASS+Team%22">for NCI-COMPASS Team</searchLink><br /><searchLink fieldCode="CA" term="%22for+NCI-MATCH+Designated+Laboratories%22">for NCI-MATCH Designated Laboratories</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229502500%22">Clinical cancer research : an official journal of the American Association for Cancer Research</searchLink> [Clin Cancer Res] 2025 Aug 14; Vol. 31 (16), pp. 3512-3525. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+Cancer+Research%22">American Association for Cancer Research </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9502500 <i>Publication Model: </i>Print <i>Cited Medium: </i>Internet <i>ISSN: </i>1557-3265 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2210780432%22">10780432 </searchLink><i>NLM ISO Abbreviation: </i>Clin Cancer Res <i>Subsets: </i>MEDLINE |
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