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Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI.

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Title: Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI.
Authors: Baritello O; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany., Sündermann SH; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.; Charité-Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany., Espinosa-Garnica K; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany., Kempfert J; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.; Charité-Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany., Jähnert M; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Beetz NL; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.; Department of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Germany Berlin Institute of Health, Berlin, Germany., Geisel D; Department of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany., Gaugel J; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Rominger J; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany., Müller-Werdan U; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Evangelisches Geriatriezentrum Berlin gGmbH, Berlin, Germany., Herpich C; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany., Norman K; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany., Chadt A; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Medical Faculty, Heinrich Heine University, Duesseldorf, Germany., Al-Hasani H; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Medical Faculty, Heinrich Heine University, Duesseldorf, Germany., Völler H; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany., Salzwedel A; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany., Vogel H; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Source: Journal of cachexia, sarcopenia and muscle [J Cachexia Sarcopenia Muscle] 2025 Jun; Vol. 16 (3), pp. e13846.
Publication Type: Journal Article
Journal Info: Publisher: John Wiley & Sons Ltd on behalf of Society on Sarcopenia, Cachexia and Wasting Disorders Country of Publication: Germany NLM ID: 101552883 Publication Model: Print Cited Medium: Internet ISSN: 2190-6009 (Electronic) Linking ISSN: 21905991 NLM ISO Abbreviation: J Cachexia Sarcopenia Muscle Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Transcriptomic Signature of Frailty in Older Patients With Cardiovascular Disease Undergoing Cardiac Surgery or TAVI.
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  Data: <searchLink fieldCode="AU" term="%22Baritello+O%22">Baritello O</searchLink>; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.<br /><searchLink fieldCode="AU" term="%22Sündermann+SH%22">Sündermann SH</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.; Charité-Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Espinosa-Garnica+K%22">Espinosa-Garnica K</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Kempfert+J%22">Kempfert J</searchLink>; Department of Cardiothoracic and Vascular Surgery, Deutsches Herzzentrum der Charité, Berlin, Germany.; Charité-Universitätsmedizin Berlin, Berlin, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Jähnert+M%22">Jähnert M</searchLink>; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Beetz+NL%22">Beetz NL</searchLink>; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.; Department of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, BIH Biomedical Innovation Academy, Germany Berlin Institute of Health, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Geisel+D%22">Geisel D</searchLink>; Department of Radiology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Gaugel+J%22">Gaugel J</searchLink>; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Rominger+J%22">Rominger J</searchLink>; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Müller-Werdan+U%22">Müller-Werdan U</searchLink>; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Evangelisches Geriatriezentrum Berlin gGmbH, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Herpich+C%22">Herpich C</searchLink>; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany.<br /><searchLink fieldCode="AU" term="%22Norman+K%22">Norman K</searchLink>; Department of Geriatrics and Medical Gerontology, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Nutrition and Gerontology, German Institute of Human Nutrition Potsdam-Rehbrücke, Nuthetal, Germany.; Institute of Nutritional Science, University of Potsdam, Nuthetal, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Berlin, Berlin, Germany.<br /><searchLink fieldCode="AU" term="%22Chadt+A%22">Chadt A</searchLink>; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Medical Faculty, Heinrich Heine University, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Al-Hasani+H%22">Al-Hasani H</searchLink>; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Institute for Clinical Biochemistry and Pathobiochemistry, German Diabetes Center (DDZ), Medical Faculty, Heinrich Heine University, Duesseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Völler+H%22">Völler H</searchLink>; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.<br /><searchLink fieldCode="AU" term="%22Salzwedel+A%22">Salzwedel A</searchLink>; Department of Rehabilitation Medicine, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.<br /><searchLink fieldCode="AU" term="%22Vogel+H%22">Vogel H</searchLink>; Research Group Molecular and Clinical Life Science of Metabolic Diseases, Faculty of Health Sciences Brandenburg, University of Potsdam, Potsdam, Germany.; German Center for Diabetes Research (DZD e.V.), München-Neuherberg, Munich, Germany.; Department of Experimental Diabetology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.; Research Group Nutrigenomics of Obesity, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
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