Oxygen-Generating Biomimetic Nano-Herb System for Synergistic Therapy & Pain Relief in Triple-Negative Breast Cancer via HIF-1α/VEGF Pathway.

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Title: Oxygen-Generating Biomimetic Nano-Herb System for Synergistic Therapy & Pain Relief in Triple-Negative Breast Cancer via HIF-1α/VEGF Pathway.
Authors: Cao DC; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of General Surgery, the second Medical College, Yantai Affiliated Hospital, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Shandong Laboratory of Advanced Materials and Green Manufacturing, Yantai, Shandong, 264000, People's Republic of China., Liang Y; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of Oncology, Binzhou Medical University Affiliated Hospital of Traditional Chinese Medicine, Binzhou, Shandong, 256600, People's Republic of China., Guo Y; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Wu DY; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Wang NN; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Li YM; Department of Immune Rheumatism, Yantaishan Hospital, Yantai, Shandong, 264000, People's Republic of China., Sun HF; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Wang Q; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Zhang X; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Chi YL; Department of Anesthesiology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250011, People's Republic of China., Sun PP; Department of Oncology, Binzhou Medical University Affiliated Hospital of Traditional Chinese Medicine, Binzhou, Shandong, 256600, People's Republic of China., Li YJ; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Wang RR; Department of Rehabilitation Engineering, Institute of Rehabilitation Medicine, School of Rehabilitation Medicine, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Wang PY; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of Epidemiology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China., Xie SY; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of General Surgery, the second Medical College, Yantai Affiliated Hospital, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Shandong Laboratory of Advanced Materials and Green Manufacturing, Yantai, Shandong, 264000, People's Republic of China., Xie N; Department of Chest Surgery, Binzhou Medical University Affiliated Yantaishan Hospital, Yantai, Shandong, 264000, People's Republic of China.
Source: International journal of nanomedicine [Int J Nanomedicine] 2025 May 31; Vol. 20, pp. 7113-7132. Date of Electronic Publication: 2025 May 31 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: DOVE Medical Press Country of Publication: New Zealand NLM ID: 101263847 Publication Model: eCollection Cited Medium: Internet ISSN: 1178-2013 (Electronic) Linking ISSN: 11769114 NLM ISO Abbreviation: Int J Nanomedicine Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cao+DC%22">Cao DC</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of General Surgery, the second Medical College, Yantai Affiliated Hospital, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Shandong Laboratory of Advanced Materials and Green Manufacturing, Yantai, Shandong, 264000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liang+Y%22">Liang Y</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of Oncology, Binzhou Medical University Affiliated Hospital of Traditional Chinese Medicine, Binzhou, Shandong, 256600, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Guo+Y%22">Guo Y</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+DY%22">Wu DY</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+NN%22">Wang NN</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+YM%22">Li YM</searchLink>; Department of Immune Rheumatism, Yantaishan Hospital, Yantai, Shandong, 264000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Sun+HF%22">Sun HF</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+Q%22">Wang Q</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Zhang+X%22">Zhang X</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Chi+YL%22">Chi YL</searchLink>; Department of Anesthesiology, Affiliated Hospital of Shandong University of Traditional Chinese Medicine, Jinan, 250011, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Sun+PP%22">Sun PP</searchLink>; Department of Oncology, Binzhou Medical University Affiliated Hospital of Traditional Chinese Medicine, Binzhou, Shandong, 256600, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Li+YJ%22">Li YJ</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+RR%22">Wang RR</searchLink>; Department of Rehabilitation Engineering, Institute of Rehabilitation Medicine, School of Rehabilitation Medicine, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wang+PY%22">Wang PY</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of Epidemiology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xie+SY%22">Xie SY</searchLink>; Department of Biochemistry and Molecular Biology, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Department of General Surgery, the second Medical College, Yantai Affiliated Hospital, Binzhou Medical University, Yantai, Shandong, 264003, People's Republic of China.; Shandong Laboratory of Advanced Materials and Green Manufacturing, Yantai, Shandong, 264000, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Xie+N%22">Xie N</searchLink>; Department of Chest Surgery, Binzhou Medical University Affiliated Yantaishan Hospital, Yantai, Shandong, 264000, People's Republic of China.
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  Data: <searchLink fieldCode="JN" term="%22101263847%22">International journal of nanomedicine</searchLink> [Int J Nanomedicine] 2025 May 31; Vol. 20, pp. 7113-7132. <i>Date of Electronic Publication: </i>2025 May 31 (<i>Print Publication: </i>2025).
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