Redox signaling-mediated S-glutathionylation of protein disulfide isomerase A1 initiates intrinsic apoptosis and contributes to accelerated aging.

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Bibliographic Details
Title: Redox signaling-mediated S-glutathionylation of protein disulfide isomerase A1 initiates intrinsic apoptosis and contributes to accelerated aging.
Authors: Ye ZW; Department of Pharmacology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, SC29425, USA., Zhang J; Department of Pharmacology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, SC29425, USA., Kumar A; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY14203, USA., Huang X; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY14203, USA., Mathuram TL; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY14203, USA., Mccall AD; Confocal Microscopy Facility, School of Dental Medicine, University at Buffalo, NY14215, USA., Culpepper J; Department of Pharmacology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, SC29425, USA., Zhang L; Department of Pharmacology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, SC29425, USA., Curione AD; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY14203, USA., Xu J; School of Life and Pharmaceutical Sciences (LPS) and Panjin Institute of Industrial Technology (PIIT), Dalian University of Technology, Panjin, China., Tew KD; Department of Pharmacology and Immunology, College of Medicine, Medical University of South Carolina, Charleston, SC29425, USA., Townsend DM; Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, Medical University of South Carolina, Charleston, SC29425, USA. Electronic address: townsed@musc.edu., Blumental-Perry A; Department of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, University at Buffalo, NY14203, USA. Electronic address: annablum@buffalo.edu.
Source: Redox biology [Redox Biol] 2025 Sep; Vol. 85, pp. 103680. Date of Electronic Publication: 2025 May 27.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2213-2317
DOI:10.1016/j.redox.2025.103680