The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling.

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Title: The TRIP12 E3 ligase induces SWI/SNF component BRG1-β-catenin interaction to promote Wnt signaling.
Authors: Kassel S; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Yuan K; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Bunnag N; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Department of Biochemistry and Cell Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Neitzel LR; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Lu W; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Schwarzkopf A; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Maines B; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Loberg MA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Xu G; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Adams A; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., McCray AD; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Cho A; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Rockouski M; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Orton G; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Goldsmith L; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA., Aronno MMA; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Spencer ZT; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA., Khan OM; Division of Biological and Biomedical Sciences, College of Health and Life Sciences, Hamad Bin Khalifa University, Doha, Qatar., Ye F; Department of Biostatistics, Vanderbilt University Medical Center, Nashville, TN, USA., Williams C; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Lebensohn AM; Laboratory of Cellular and Molecular Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA., Rohatgi R; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA, USA., Wang X; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA., Weiss VL; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN, USA., Hong CC; Department of Medicine, Michigan State University College of Human Medicine, East Lansing, MI, USA., Kettenbach AN; Department of Biochemistry and Cell Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA., Robbins DJ; Department of Oncology, Lombardi Comprehensive Cancer Center, Georgetown University, Washington, DC, USA., Ahmed Y; Department of Molecular and Systems Biology, Geisel School of Medicine, Dartmouth College, Hanover, NH, USA. yashi.ahmed@dartmouth.edu.; Dartmouth Cancer Center, Dartmouth College, Lebanon, NH, USA. yashi.ahmed@dartmouth.edu., Lee E; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, TN, USA. ethan.lee@vanderbilt.edu.; Vanderbilt Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN, USA. ethan.lee@vanderbilt.edu.
Source: Nature communications [Nat Commun] 2025 Jun 05; Vol. 16 (1), pp. 5248. Date of Electronic Publication: 2025 Jun 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:2041-1723
DOI:10.1038/s41467-025-60535-5