Unlocking the serine mischarging paradox and inhibiting lactyltransferase activity of AlaRS by a single-point mutation.
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| Title: | Unlocking the serine mischarging paradox and inhibiting lactyltransferase activity of AlaRS by a single-point mutation. |
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| Authors: | Park W; Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea., Son SY; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea., Yi J; Doping Control Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.; Interdisciplinary Program for Biochemical Engineering and Biotechnology, Seoul National University, Seoul 08826, Republic of Korea., Cha S; Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea., Moon H; Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea., Kim M; Doping Control Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea.; Interdisciplinary Program for Biochemical Engineering and Biotechnology, Seoul National University, Seoul 08826, Republic of Korea., Ji S; Department of Brain Sciences, DGIST, Daegu 42988, Republic of Korea., Yu W; Department of Brain Sciences, DGIST, Daegu 42988, Republic of Korea., Sung C; Doping Control Center, Korea Institute of Science and Technology, Seoul 02792, Republic of Korea., Cha SS; Department of Chemistry & Nanoscience, Ewha Womans University, Seoul 03760, Republic of Korea.; Graduate Program in Innovative Biomaterials Convergence, Ewha Womans University, Seoul 03760, Republic of Korea., Hahn JS; Department of Chemical and Biological Engineering, Institute of Chemical Processes, Seoul National University, Seoul 08826, Republic of Korea.; Interdisciplinary Program for Biochemical Engineering and Biotechnology, Seoul National University, Seoul 08826, Republic of Korea. |
| Source: | Nucleic acids research [Nucleic Acids Res] 2025 Jun 06; Vol. 53 (11). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1362-4962 |
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| DOI: | 10.1093/nar/gkaf462 |
