Development of Mutant M3 Muscarinic Receptors Biased for G Protein Activation or Recruitment of β-Arrestins.
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| Title: | Development of Mutant M |
|---|---|
| Authors: | Meister J; Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, United States.; Institute for Clinical Diabetology, German Diabetes Center, Leibniz Institute for Diabetes Research at Heinrich Heine University, Düsseldorf 40225, Germany., Wanka L; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig 04109, Germany., Perry-Hauser NA; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Liu L; Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, United States., Iverson TM; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Gurevich VV; Department of Pharmacology, Vanderbilt University, Nashville, Tennessee 37232, United States., Beck-Sickinger AG; Institute of Biochemistry, Faculty of Life Sciences, Leipzig University, Leipzig 04109, Germany., Kruse AC; Department of Biological Chemistry and Molecular Pharmacology, Blavatnik Institute, Harvard Medical School, Boston, Massachusetts 02115, United States., Wess J; Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, Maryland 20892, United States. |
| Source: | Biochemistry [Biochemistry] 2025 Jul 01; Vol. 64 (13), pp. 2727-2736. Date of Electronic Publication: 2025 Jun 09. |
| Publication Type: | Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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