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Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.

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Bibliographic Details
Title:	Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.
Authors:	Grund EM; Mayo Graduate School.; Mayo Clinic Medical Scientist Training Program.; Translational Neuroimmunology Laboratory., Clarkson BD; Translational Neuroimmunology Laboratory.; Department of Laboratory Medicine and Pathology.; Center for Multiple Sclerosis and Autoimmune Neurology., Pucci S; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Westphal MS; Translational Neuroimmunology Laboratory., Partida CM; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Muhammad SA; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Howe CL; Translational Neuroimmunology Laboratory.; Center for Multiple Sclerosis and Autoimmune Neurology.; Department of Neurology, and.; Division of Experimental Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Source:	JCI insight [JCI Insight] 2025 Jun 10; Vol. 10 (14). Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type:	Journal Article
Journal Info:	Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database:	MEDLINE Ultimate

Description
ISSN:	2379-3708
DOI:	10.1172/jci.insight.184240