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Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.

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Title: Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.
Authors: Grund EM; Mayo Graduate School.; Mayo Clinic Medical Scientist Training Program.; Translational Neuroimmunology Laboratory., Clarkson BD; Translational Neuroimmunology Laboratory.; Department of Laboratory Medicine and Pathology.; Center for Multiple Sclerosis and Autoimmune Neurology., Pucci S; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Westphal MS; Translational Neuroimmunology Laboratory., Partida CM; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Muhammad SA; Translational Neuroimmunology Laboratory.; Department of Neurology, and., Howe CL; Translational Neuroimmunology Laboratory.; Center for Multiple Sclerosis and Autoimmune Neurology.; Department of Neurology, and.; Division of Experimental Neurology, Mayo Clinic, Rochester, Minnesota, USA.
Source: JCI insight [JCI Insight] 2025 Jun 10; Vol. 10 (14). Date of Electronic Publication: 2025 Jun 10 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: eCollection Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Pentose phosphate pathway inhibition metabolically reprograms CD8+ T cells and disrupts CNS autoimmunity.
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  Data: <searchLink fieldCode="AU" term="%22Grund+EM%22">Grund EM</searchLink>; Mayo Graduate School.; Mayo Clinic Medical Scientist Training Program.; Translational Neuroimmunology Laboratory.<br /><searchLink fieldCode="AU" term="%22Clarkson+BD%22">Clarkson BD</searchLink>; Translational Neuroimmunology Laboratory.; Department of Laboratory Medicine and Pathology.; Center for Multiple Sclerosis and Autoimmune Neurology.<br /><searchLink fieldCode="AU" term="%22Pucci+S%22">Pucci S</searchLink>; Translational Neuroimmunology Laboratory.; Department of Neurology, and.<br /><searchLink fieldCode="AU" term="%22Westphal+MS%22">Westphal MS</searchLink>; Translational Neuroimmunology Laboratory.<br /><searchLink fieldCode="AU" term="%22Partida+CM%22">Partida CM</searchLink>; Translational Neuroimmunology Laboratory.; Department of Neurology, and.<br /><searchLink fieldCode="AU" term="%22Muhammad+SA%22">Muhammad SA</searchLink>; Translational Neuroimmunology Laboratory.; Department of Neurology, and.<br /><searchLink fieldCode="AU" term="%22Howe+CL%22">Howe CL</searchLink>; Translational Neuroimmunology Laboratory.; Center for Multiple Sclerosis and Autoimmune Neurology.; Department of Neurology, and.; Division of Experimental Neurology, Mayo Clinic, Rochester, Minnesota, USA.
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  Data: <searchLink fieldCode="JN" term="%22101676073%22">JCI insight</searchLink> [JCI Insight] 2025 Jun 10; Vol. 10 (14). <i>Date of Electronic Publication: </i>2025 Jun 10 (<i>Print Publication: </i>2025).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Society+for+Clinical+Investigation%22">American Society for Clinical Investigation </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101676073 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2379-3708 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223793708%22">23793708 </searchLink><i>NLM ISO Abbreviation: </i>JCI Insight <i>Subsets: </i>MEDLINE
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        Value: 10.1172/jci.insight.184240
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              Text: 2025 Jun 10
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