Differential susceptibility and role for senescence in CART cells based on costimulatory domains.
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| Title: | Differential susceptibility and role for senescence in CART cells based on costimulatory domains. |
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| Authors: | Can I; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Siegler EL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Sirpilla OL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Manriquez-Roman C; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA., Yun K; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Stewart CM; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Feigin JM; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA., Rodriguez ML; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Gutierrez-Ruiz OL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Ogbodo EJ; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Huynh TN; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Kimball BL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Mai LK; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Hefazi M; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Fonkoua LK; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Department of Oncology, Mayo Clinic, Rochester, MN, USA., Xia H; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Hamaidi I; Cancer Biology, Mayo Clinic, Jacksonville, FL, USA., Alkan B; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Sezer F; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Ekiz HA; Department of Molecular Biology and Genetics, Izmir Institute of Technology, Izmir, Türkiye., Sakemura RL; T Cell Engineering, Mayo Clinic, Rochester, MN, USA.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA., Kenderian SS; T Cell Engineering, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu.; Division of Hematology, Mayo Clinic, 200 First Street S.W, Rochester, MN, 55905, USA. kenderian.saad@mayo.edu.; Mayo Clinic Graduate School of Biomedical Sciences, Rochester, MN, USA. kenderian.saad@mayo.edu.; Center for Regenerative Biotherapeutics, Mayo Clinic, Rochester, MN, USA. kenderian.saad@mayo.edu. |
| Source: | Molecular cancer [Mol Cancer] 2025 Jun 10; Vol. 24 (1), pp. 172. Date of Electronic Publication: 2025 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Country of Publication: England NLM ID: 101147698 Publication Model: Electronic Cited Medium: Internet ISSN: 1476-4598 (Electronic) Linking ISSN: 14764598 NLM ISO Abbreviation: Mol Cancer Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1476-4598 |
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| DOI: | 10.1186/s12943-025-02371-1 |
