Integration of single-cell and spatial transcriptomics by SEU-TCA reveals the spatial origin of early cardiac progenitors.
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| Title: | Integration of single-cell and spatial transcriptomics by SEU-TCA reveals the spatial origin of early cardiac progenitors. |
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| Authors: | He J; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China., Yang Y; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China.; Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China., Jiang R; Institute for Regenerative Medicine, State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Shanghai East Hospital, Tongji University, Shanghai, China., Zheng Y; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China., Yang X; Guangzhou Laboratory, Guangzhou, China., Jiang X; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China., Xue X; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China., Yang Z; State Key Laboratory of Pharmaceutical Biotechnology, Department of Cardiology, Model Animal Research Center, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School and MOE Key Laboratory of Model Animal for Disease Study, Nanjing University, Nanjing, China., Jing N; Guangzhou Laboratory, Guangzhou, China., Cao H; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China. shuqu_1982@sina.com., Luo Z; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China. zjluo@seu.edu.cn., Wei K; Institute for Regenerative Medicine, State Key Laboratory of Cardiology and Medical Innovation Center, Shanghai Key Laboratory of Signaling and Disease Research, Frontier Science Center for Stem Cell Research, School of Life Sciences and Technology, Shanghai East Hospital, Tongji University, Shanghai, China. kewei@tongji.edu.cn., Xie P; State Key Laboratory of Digital Medical Engineering, School of Biological Science & Medical Engineering, Southeast University, Nanjing, China. pengx@seu.edu.cn., Lin C; Department of Cardiac Surgery, Key Laboratory of Developmental Genes and Human Disease, School of Life Science and Technology, Zhongda Hospital, Southeast University, Nanjing, China. cqlin@seu.edu.cn.; Co-Innovation Center of Neuroregeneration, Nantong University, Nantong, China. cqlin@seu.edu.cn. |
| Source: | Genome biology [Genome Biol] 2025 Jun 10; Vol. 26 (1), pp. 158. Date of Electronic Publication: 2025 Jun 10. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1474-760X |
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| DOI: | 10.1186/s13059-025-03633-3 |
