trans-Cyclooctene-caged-IL-1β immunocytokine-constructs ligated to unmodified nanobodies allow click-2-release-based control of cytokine activity.
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| Title: | trans-Cyclooctene-caged-IL-1β immunocytokine-constructs ligated to unmodified nanobodies allow click-2-release-based control of cytokine activity. |
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| Authors: | Barendrecht A; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., Peeters HHC; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., Torres-García D; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., Shema MT; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., Sarris AJC; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., David S; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl., Aba G; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl.; Leiden University Medical Center Albinusdreef 2 Leiden The Netherlands., Le Gall CM; Department of Medical BioSciences, Radboud University Medical Center Nijmegen The Netherlands., Wilkovitsch M; Institute of Applied Synthetic Chemistry, TU Wien Getreidemarkt 9/163 Vienna Austria., Verdoes M; Department of Medical BioSciences, Radboud University Medical Center Nijmegen The Netherlands.; Institute for Chemical Immunology Nijmegen The Netherlands.; Current address: Department of Immunology, Leiden University Medical Center Leiden The Netherlands., Mikula H; Institute of Applied Synthetic Chemistry, TU Wien Getreidemarkt 9/163 Vienna Austria., Travis MA; Manchester Collaborative Centre for Inflammation Research, University of Manchester Manchester UK., van Kasteren SI; Division of Chemical Biology and Immunology, Leiden Institute of Chemistry, Universiteit Leiden Gorlaeus Laboratory, Einsteinweg 55 Leiden The Netherlands s.i.van.kasteren@chem.leidenuniv.nl. |
| Source: | RSC chemical biology [RSC Chem Biol] 2025 Jun 04; Vol. 6 (7), pp. 1068-1078. Date of Electronic Publication: 2025 Jun 04 (Print Publication: 2025). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
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